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Merck
CN

71778

Sigma-Aldrich

硝普钠 二水合物

puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99%

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别名:
SNP, 五氰基亚硝酰基铁酸钠, 亚硝基铁氰化钠, 硝普酸钠
线性分子式:
Na2[Fe(CN)5NO] · 2H2O
CAS号:
分子量:
297.95
EC 号:
MDL编号:
UNSPSC代码:
12352300
PubChem化学物质编号:
NACRES:
NB.24

等级

ACS reagent
puriss. p.a.

质量水平

Agency

reag. Ph. Eur.
suitable for SM 4500 - NH3

检测方案

≥99%

形式

crystals or chunks

溶解性

water: soluble(lit.)

痕量阴离子

chloride (Cl-): ≤100 mg/kg
hexacyanoferrate(II) ([Fe(CN)6]4-): ≤200 mg/kg
hexacyanoferrate(III) ([Fe(CN)6]3-): ≤100 mg/kg
sulfate (SO42-): ≤100 mg/kg

痕量阳离子

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤50 mg/kg
Cu: ≤5 mg/kg
K: ≤3000 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤50 mg/kg

SMILES字符串

O.O.[Na+].[Na+].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N

InChI

1S/5CN.Fe.NO.2Na.2H2O/c5*1-2;;1-2;;;;/h;;;;;;;;;2*1H2/q;;;;;2*-1;2*+1;;

InChI key

OIRZWVYIQXBRFC-UHFFFAOYSA-N

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一般描述

硝普钠二水合物(五氰基亚硝酰基铁(2-)酸钠二水合物,SNP)分子含有一个亚铁离子中心,其被五个氰化物基团和亚硝酰基包围。硝普钠具有临床应用价值。它可用作一种快速起效的血管扩张剂。它还被广泛用作各种实验模型的一氧化氮(NO)供体。已经鉴定了硝普钠二水合物Na2[Fe(CN)5NO].2H2O的两种亚稳态,并且已通过X射线衍射研究了它们的几何形状。

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Diffraction studies of photoexcited crystals: Metastable nitrosyl-linkage isomers of sodium nitroprusside.
Carducci MD, et al.
Journal of the American Chemical Society, 119(11), 2669-2678 (1997)
M Chiusa et al.
European journal of histochemistry : EJH, 56(2), e15-e15 (2012-06-13)
Sodium nitroprusside (SNP) is used clinically as a rapid-acting vasodilator and in experimental models as donor of nitric oxide (NO). High concentrations of NO have been reported to induce cardiotoxic effects including apoptosis by the formation of reactive oxygen species.
Mariko Takahashi et al.
Science signaling, 12(564) (2019-01-17)
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Arthritis research & therapy, 13(3), R99-R99 (2011-06-23)
Patients with rheumatoid arthritis (RA) are at an increased risk for cardiovascular disease (CVD). One of the earliest manifestations of CVD is endothelial dysfunction (ED). ED can occur in both the microcirculation and the macrocirculation, and these manifestations might be
Mahboobe Ghaedi et al.
The Journal of clinical investigation, 123(11), 4950-4962 (2013-10-19)
The use of induced pluripotent stem cells (iPSCs) has been postulated to be the most effective strategy for developing patient-specific respiratory epithelial cells, which may be valuable for lung-related cell therapy and lung tissue engineering. We generated a relatively homogeneous

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