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Merck
CN

307432

Sigma-Aldrich

1,2-二甲氧基乙烷

suitable for HPLC, 99.9%, inhibitor-free

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别名:
1,2-二甲氧基乙烷, mono-Glyme, 乙二醇二甲醚, 单甘醇二甲醚
线性分子式:
CH3OCH2CH2OCH3
CAS号:
分子量:
90.12
Beilstein:
1209237
EC 号:
MDL编号:
UNSPSC代码:
12190000
PubChem化学物质编号:
NACRES:
NA.21

蒸汽密度

3.1 (20 °C, vs air)

质量水平

蒸汽压

48 mmHg ( 20 °C)

检测方案

99.9%

形式

liquid

自燃温度

396 °F

纯化方式

glass distillation

expl. lim.

10.4 %

技术

HPLC: suitable

杂质

<0.030% water

折射率

n20/D 1.379 (lit.)

pH值(酸碱度)

~7

bp

85 °C (lit.)

mp

−58 °C (lit.)

密度

0.867 g/mL at 25 °C (lit.)

λ

H2O reference

紫外吸收

λ: 220 nm Amax: 1.00
λ: 250 nm Amax: 0.20
λ: 300 nm Amax: 0.03
λ: 350-400 nm Amax: 0.01

应用

food and beverages

SMILES字符串

COCCOC

InChI

1S/C4H10O2/c1-5-3-4-6-2/h3-4H2,1-2H3

InChI key

XTHFKEDIFFGKHM-UHFFFAOYSA-N

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一般描述

该溶剂经过玻璃蒸馏、亚微米过滤并经过严格的规格测试以保证各批次一致。

应用

为HPLC仪器和有机合成应用而设计。

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警示用语:

Danger

危险分类

Acute Tox. 4 Inhalation - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2

补充剂危害

WGK

WGK 1

闪点(°F)

closed cup

闪点(°C)

closed cup

法规信息

危险化学品

分析证书(COA)

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NMR Chemical Shifts of Common Laboratory Solvents as Trace Impurities.
Hugo E. Gottlieb et al.
The Journal of organic chemistry, 62(21), 7512-7515 (2001-10-24)
Theoretical study of cation/ether complexes: Alkali metal cations with 1, 2-dimethoxyethane and 12-crown-4.
Hill SE, et al.
The Journal of Physical Chemistry A, 102(21), 3813-3819 (1998)
The catalytic Pauson-Khand reaction promoted by a small amount of 1, 2-dimethoxyethane or water.
Sugihara T and Yamaguchi M.
Synlett, 12, 1384-1386 (1998)
Andrew Martins et al.
Organic letters, 12(22), 5186-5188 (2010-10-19)
A palladium-catalyzed crossed biaryl coupling/reduction sequence enables the formation of meta-substituted biaryls via solvent-mediated arylpalladium(II) reduction. Isotope labeling studies determined that the decomposition of 1,2-dimethoxyethane (DME) is indeed involved in the reductive process.
Peter A Campochiaro et al.
Ophthalmology, 122(3), 545-554 (2014-12-03)
AKB-9778 is a small-molecule competitive inhibitor of vascular endothelial-protein tyrosine phosphatase (VE-PTP) that promotes Tie2 activation and reduces vascular leakage and neovascularization in mouse models. The purpose of this study was to test the safety, tolerability, pharmacokinetics, and biological activity

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