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经验公式(希尔记法):
C16H24N2O · HCl
化学文摘社编号:
分子量:
296.84
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
产品名称
峰鉴别3用罗匹尼罗, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C16H24N2O.ClH/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15;/h5-7H,3-4,8-12H2,1-2H3,(H,17,19);1H
SMILES string
Cl.CCCN(CCC)CCc1cccc2NC(=O)Cc12
InChI key
XDXHAEQXIBQUEZ-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
ropinirole
manufacturer/tradename
EDQM
format
neat
storage temp.
2-8°C
Gene Information
human ... DRD2(1813), DRD3(1814), DRD4(1815)
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Application
Ropinirole for peak identification 3 EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Biochem/physiol Actions
An agonist at the D2 and D3 dopamine receptor subtypes, binding with higher affinity to D3 than to D2 or D4. It has negligible effect on D1-receptors. It has medium in vitro affinity to opioid receptors. Ropinirole is said to have virtually no affinity to 5-HT1, 5-HT2, benzodiazepine, GABA, muscarinic, α1-, α2-, and β-adrenoreceptors. Used as antiparkinsonian drug.
Selective D2 dopamine receptor agonist, antiparkinsonian
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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