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Merck
CN
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主要文件

Y0001649

阿立哌唑

European Pharmacopoeia (EP) Reference Standard

别名:

7-{4-[4-(2,3-二氯苯基)-L-哌嗪基]丁氧基}-3,4-二氢-2(1H)-喹啉酮

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About This Item

经验公式(希尔记法):
C23H27Cl2N3O2
分子量:
448.39
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

aripiprazole

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

InChI

1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)

InChI key

CEUORZQYGODEFX-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Aripiprazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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分析证书(COA)

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Daniel J Safer et al.
Journal of child and adolescent psychopharmacology, 23(4), 282-289 (2013-05-08)
This study aimed to: document the extent of the reduction of serum prolactin (PRL) levels induced by aripiprazole (ARI) treatment in children and adolescents, compare this effect by age group, and shed light on this phenomenon. PRL serum levels in
M Brunetti et al.
European review for medical and pharmacological sciences, 16(10), 1346-1354 (2012-10-30)
Aripiprazole is an atypical antipsychotic used for schizophrenia, manic and mixed episodes associated with bipolar I disorder and as adjunctive therapy for major depressive disorder. It functions as a partial agonist at dopamine D2 and 5-HT1A receptors, and as an
Farouq I Thabet et al.
Clinical neuropharmacology, 36(1), 29-30 (2013-01-22)
Aripiprazole is an atypical antipsychotic medication that is a partial dopamine D(2) and serotonin 5-hydroxytryptamine (1A) receptor agonist and 5-hydroxytryptamine (2A) receptor antagonist. It has a safer profile compared to other antipsychotic medications with regard to its effect on weight
Mariusz Papp et al.
Behavioural pharmacology, 25(5-6), 567-574 (2014-08-02)
The aim of this study was to evaluate whether chronic treatment with cariprazine, a dopamine D2 and D3 receptor partial agonist with preferential binding to D3 receptors, shows antidepressant-like effects in the chronic mild stress (CMS)-induced anhedonia model. Male Wistar
Hiroyoshi Takeuchi et al.
Psychopharmacology, 228(2), 175-185 (2013-06-06)
Numerous case reports have suggested that aripiprazole can worsen psychotic symptoms in schizophrenia. We reviewed reported cases which have suggested that aripiprazole can worsen psychotic symptoms in schizophrenia and evaluated each regarding quality of the causal relationship. A systematic literature

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