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Merck
CN

Y0001647

Vardenafil hydrochloride trihydrate

European Pharmacopoeia (EP) Reference Standard

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About This Item

经验公式(希尔记法):
C23H32N6O4S · HCl · 3H2O
分子量:
579.11
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

vardenafil

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

CCOC1=CC=C(S(N2CCN(CC)CC2)(=O)=O)C=C1C3=NN4C(C(N3)=O)=C(C)N=C4CCC.Cl

InChI

1S/C23H32N6O4S.ClH.3H2O/c1-5-8-20-24-16(4)21-23(30)25-22(26-29(20)21)18-15-17(9-10-19(18)33-7-3)34(31,32)28-13-11-27(6-2)12-14-28;;;;/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,30);1H;3*1H2

InChI key

FBCDRHDULQYRTB-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Vardenafil hydrochloride trihydrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral - STOT RE 2

靶器官

Cardio-vascular system

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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Identification of sildenafil, tadalafil and vardenafil by gas chromatography?mass spectrometry on short capillary column.
Man C N, et al.
Journal of Chromatography A, 1216(47), 8426-8430 (2009)
Hilary A Kenny et al.
Molecular cancer therapeutics, 19(1), 52-62 (2019-09-29)
The tumor microenvironment (TME) is a key determinant of metastatic efficiency. We performed a quantitative high-throughput screen (qHTS) of diverse medicinal chemistry tractable scaffolds (44,420 compounds) and pharmacologically active small molecules (386 compounds) using a layered organotypic, robust assay representing
Yuehui Zhu et al.
Infection and immunity, 86(11) (2018-08-22)
Enterotoxigenic Escherichia coli (ETEC), a heterogeneous diarrheal pathovar defined by production of heat-labile (LT) and/or heat-stable (ST) toxins, causes substantial morbidity among young children in the developing world. Studies demonstrating a major burden of ST-producing ETEC have focused interest on

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