推荐产品
生物来源
synthetic
等级
pharmaceutical primary standard
Agency
EP
API类
ciclesonide
包装
pkg of 15 mg
制造商/商品名称
EDQM
储存条件
protect from light
颜色
white
沸点
665.0 °C/1.333 hPa (1229.0°F)
mp
209-211 °C (408—412°F)
溶解性
water: <0.1 g/L
acetone: soluble
ethanol: soluble
密度
1.23 g/cm3 at 20 °C (1.333 hPa)
应用
pharmaceutical (small molecule)
包装形式
neat
运输
ambient
储存温度
2-8°C
一般描述
Ciclesonide is a new-generation, non-halogenated glucocorticoid. It is a prodrug that releases an active primary metabolite, ciclesonide−active principle (CIC-AP), on enzymatic cleavage.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Ciclesonide containing impurity A is used as an EP reference standard to quantify the analyte in pharmaceutical formulations by liquid chromatography (LC) technique.
包装
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他说明
Sales restrictions may apply.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
New Drugs for Asthma, Allergy and COPD, 42, 42-54 (2001)
Population pharmacokinetics and pharmacodynamics of ciclesonide
Rohatagi S, et al.
Journal of Clinical Pharmacology, 43(4), 365-378 (2003)
Ciclesonide
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 43, 2206-2207 (2017)
Pharmacokinetics of [14 C] ciclesonide after oral and intravenous administration to healthy subjects
Nave R, et al.
Clinical Pharmacokinetics, 43, 479-486 (2004)
Rethinking Cleaning Validation for API Manufacturing
Zhang C, et al.
Pharmaceutical Technology, 42, 42-54 (2018)
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