产品名称
乙酰磺胺嘧啶, European Pharmacopoeia (EP) Reference Standard
SMILES string
[S](=O)(=O)(Nc2ncccn2)c1ccc(cc1)NC(=O)C
InChI
1S/C12H12N4O3S/c1-9(17)15-10-3-5-11(6-4-10)20(18,19)16-12-13-7-2-8-14-12/h2-8H,1H3,(H,15,17)(H,13,14,16)
InChI key
NJIZUWGMNCUKGU-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
sulfadiazine
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Application
Acetylsulfadiazine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Christiane Zarfl et al.
Chemosphere, 77(6), 720-726 (2009-09-22)
Sulfadiazine (SDZ) belongs to the chemical class of sulfonamides, one of the most important groups of antibiotics applied in animal husbandry in Europe. These antibiotics end up in the soil after manure from treated animals is applied as fertilizer. They
Sulfadiazine/N4-acetylsulfadiazine crystalluria in a patient with the acquired immune deficiency syndrome (AIDS)
J L Potter et al.
Clinica chimica acta; international journal of clinical chemistry, 230(2), 221-224 (1994-10-31)
T Bergan et al.
Chemotherapy, 32(6), 478-485 (1986-01-01)
The study was aimed at analyzing the pharmacokinetics of sulphadiazine (SDZ) and trimethoprim (TMP) in geriatric patients and was carried out in two stages. The first stage compared 11 geriatric patients (68-89 years old) and 9 healthy volunteers (21-34 years
The case: 69 year old man with sand in the urine. N-acetylsulfadiazine crystals.
A K Schuler et al.
Kidney international, 72(6), 769-770 (2007-09-07)
D Westerlund et al.
Journal of pharmaceutical sciences, 71(10), 1142-1145 (1982-10-01)
Sulfadiazine and N4-acetylsulfadiazine were determined in biological fluids by the direct injection (plasma after protein precipitation and urine after dilution 100 times) of 20 microliters on a silica gel column. The mobile phase was an aqueous citrate buffer (pH 4.0)
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