推荐产品
等级
pharmaceutical primary standard
API类
minoxidil
制造商/商品名称
EDQM
mp
272-274 °C (dec.) (lit.)
应用
pharmaceutical (small molecule)
格式
neat
储存温度
2-8°C
SMILES字符串
NC1=CC(=NC(=N)N1O)N2CCCCC2
InChI
1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2
InChI key
ZIMGGGWCDYVHOY-UHFFFAOYSA-N
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一般描述
本品按现行药典规定交付。该产品的所有支持信息，包括SDS和任何产品信息宣传页均由药典发行机构制定并发布。如需更多信息和支持，请见现行药典的网站。
应用
用于系统适用性的米诺地尔EP参考标准品的预期用途是欧洲药典规定的实验室测试。
生化/生理作用
激活 ATP 激活的 K+ 通道；血管扩张剂；减缓或停止脱发，促进头发再生。
包装
本品按照现行药典要求提供。有关当前单位数量，请见EDQM 参考目录。
其他说明
可能适用相应的销售限制条件。
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
D A Sica et al.
Journal of clinical hypertension (Greenwich, Conn.), 3(2), 110-114 (2001-06-21)
Minoxidil is a direct vasodilator that has been in use for over two decades. It is used primarily to reduce blood pressure in hypertensives who have been poorly controlled on various multidrug regimens. Although minoxidil is extremely effective, its usefulness
Susumu Otomo
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 119(3), 167-174 (2002-03-28)
The length and size of hair are depend on the anagen term in its hair cycle. It has been reported that the some cell growth factors, such as VEGF, FGF-5S, IGF-1 and KGF, induce the proliferation of cells in the
R L DeVillez
Dermatologic clinics, 8(2), 367-375 (1990-04-01)
Topical minoxidil is a trichogenic agent that stimulates the hair follicle via the vasoactive metabolite minoxidil sulfate without any evidence of antiandrogen activity or an effect on the immune system. Less than 5% of the applied dose is absorbed. The
[Minoxidil. Objectivity and criticism].
F Bardazzi et al.
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 124(9), 407-409 (1989-09-01)
Alfredo Rossi et al.
Recent patents on inflammation & allergy drug discovery, 6(2), 130-136 (2012-03-14)
Minoxidil, a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth, was first introduced, exclusively as an oral drug, to treat high blood pressure. It was however discovered to have the important side-effect
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