grade
pharmaceutical primary standard
API family
vigabatrin
manufacturer/tradename
EDQM
mp
195 °C (dec.) (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
NCCCC(O)=O
InChI
1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
InChI key
BTCSSZJGUNDROE-UHFFFAOYSA-N
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Vigabatrin impurity D EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Biochem/physiol Actions
大脑中的主要抑制性神经递质；GABAA 和 GABAB 受体激动剂；增加 Cl− 的传导性。
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 17(1), 124-144 (2010-03-20)
Stress response and depression have a significant impact on modern society. Although the symptoms are well characterized, the molecular mechanisms underlying depression are largely unknown. The monoamine hypothesis, which postulates dysfunctional noradrenergic and serotonergic systems as the underlying primary cause
A D Stan et al.
Molecular psychiatry, 20(4), 433-439 (2014-06-11)
Hippocampal dysfunction in schizophrenia is widely acknowledged, yet the mechanism of such dysfunction remains debated. In this study we investigate the excitatory and inhibitory hippocampal neurotransmission using two complementary methodologies, proton magnetic resonance spectroscopy (MRS) and tissue biochemistry, sampling individuals
Melissa A Farmer et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(17), 5747-5753 (2014-04-25)
Chronic pain is often associated with sexual dysfunction, suggesting that pain can reduce libido. We find that inflammatory pain reduces sexual motivation, measured via mounting behavior and/or proximity in a paced mating paradigm, in female but not male laboratory mice.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| Y0001404 | 04061833807675 |