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文件

Y0001227

福辛普利钠

Name: 福辛普利 钠
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

(2S,4S)-4-Cyclohexyl-1-(2-{[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl}acetyl)pyrrolidine-2-carboxylic acid, Acecor, Eosinopril, Fosinopril, Monopril, SQ 28555, Secorvas, Staril

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About This Item

经验公式（希尔记法）:

C₃₀H₄₅NO₇P · Na

CAS号:

88889-14-9

分子量:

585.64

MDL编号:

MFCD23704184

UNSPSC代码:

41116107

PubChem化学物质编号:

329831315

NACRES:

NA.24

等级

pharmaceutical primary standard

API类

fosinopril

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES字符串

O=C([O-])[C@H]1N(C(CP(CCCCC2=CC=CC=C2)(O[C@@H](C(C)C)OC(CC)=O)=O)=O)C[C@H](C3CCCCC3)C1.[Na+]

InChI

1S/C30H46NO7P.Na/c1-4-28(33)37-30(22(2)3)38-39(36,18-12-11-15-23-13-7-5-8-14-23)21-27(32)31-20-25(19-26(31)29(34)35)24-16-9-6-10-17-24;/h5,7-8,13-14,22,24-26,30H,4,6,9-12,15-21H2,1-3H3,(H,34,35);/q;+1/p-1/t25-,26+,30+,39?;/m1./s1

InChI key

TVTJZMHAIQQZTL-TXDYNIFHSA-M

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Fosinopril sodium EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

生化/生理作用

Fosinopril is an angiotensin converting enzyme (ACE) inhibitor. Fosinopril is also known to inhibit the activity of the peptide transporter PEPT2.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

1283481

1283415

1283437

1283448

1283459

1283460

1283470

1283426

BP1091

福辛普利钠, British Pharmacopoeia (BP) Reference Standard

BP1092

福辛普利杂质A, British Pharmacopoeia (BP) Reference Standard

象形图

GHS08,GHS07

警示用语：

Warning

危险声明

H319,H361d

预防措施声明

P202 - P264 - P280 - P305 + P351 + P338 - P308 + P313 - P337 + P313

危险分类

Eye Irrit. 2 - Repr. 2

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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分析证书(COA)

Lot/Batch Number

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Clopidogrel bioactivation and risk of bleeding in patients cotreated with angiotensin-converting enzyme inhibitors after myocardial infarction: a proof-of-concept study.

K E Kristensen et al.

Clinical pharmacology and therapeutics, 96(6), 713-722 (2014-09-16)

Clopidogrel is an oral antiplatelet prodrug, the majority of which is hydrolyzed to an inactive metabolite by hepatic carboxylesterase 1 (CES1). Most angiotensin-converting enzyme inhibitors (ACEIs) are also metabolized by this enzyme. We examined the effects of ACEIs on clopidogrel

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福辛普利 钠