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Merck
CN

Y0001124

17α-乙炔基雌二醇

European Pharmacopoeia (EP) Reference Standard

别名:

17α-乙炔基-1,3,5(10)-雌甾三烯-1,17β-二醇, 19-去甲-1,3,5(10),17α-雌甾三烯-20-炔-3,17-二醇, 炔雌醇

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About This Item

经验公式(希尔记法):
C20H24O2
CAS号:
分子量:
296.40
Beilstein:
2419975
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

ethinylestradiol

制造商/商品名称

EDQM

mp

182-183 °C (lit.)

应用

pharmaceutical (small molecule)

包装形式

neat

SMILES字符串

[H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@@]3(O)C#C)[C@]1([H])CCc4cc(O)ccc24

InChI

1S/C20H24O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,5,7,12,16-18,21-22H,4,6,8-11H2,2H3/t16-,17-,18+,19+,20+/m1/s1

InChI key

BFPYWIDHMRZLRN-SLHNCBLASA-N

基因信息

human ... ESR1(2099)

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Ethinylestradiol for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Aquatic Chronic 1 - Carc. 2 - Repr. 1A

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jürgen Dinger et al.
Obstetrics and gynecology, 122(4), 800-808 (2013-10-03)
To compare the risks of short-term and long-term use of an etonogestrel-containing and ethinylestradiol-containing vaginal ring and combined oral contraceptive pills (OCPs) in a routine clinical study population. This was a prospective, controlled, noninterventional cohort study performed in the United
Bin Huang et al.
Environment international, 59, 262-273 (2013-07-16)
The occurrence, removal and bioaccumulation of steroid estrogens such as the natural estrone (E1), 17β-estradiol (E2) and estriol (E3), as well as the synthetic 17α-ethynylestradiol (EE2) were investigated in Dianchi Lake catchment, China. The results show that traditional secondary treatment
A Frølich et al.
Bone, 11(6), 393-396 (1990-01-01)
An attempt was made to explain the bone-preserving effect of estrogen by analysis of estrogen receptors (OER) in the calcitonin-producing C-cells of the human thyroid gland. Thyroid tissue from twenty patients with benign hyperthyroidism and three patients with medullary thyroid
Bernardine H Stegeman et al.
BMJ (Clinical research ed.), 347, f5298-f5298 (2013-09-14)
To provide a comprehensive overview of the risk of venous thrombosis in women using different combined oral contraceptives. Systematic review and network meta-analysis. PubMed, Embase, Web of Science, Cochrane, Cumulative Index to Nursing and Allied Health Literature, Academic Search Premier
C Piérard-Franchimont et al.
Maturitas, 22(2), 151-154 (1995-09-01)
The effects of menopause and hormone replacement therapy (HRT) on the epidermis are largely unknown. The aim of this study was to model and measure the influence of estrogen-transdermal HRT on subtle physiological changes taking place in the epidermis during

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