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Merck
CN
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主要文件

Y0001104

Picosulfate for system suitability

European Pharmacopoeia (EP) Reference Standard

别名:

Sodium picosulfate

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About This Item

经验公式(希尔记法):
C18H13NNa2O8S2
CAS号:
分子量:
481.41
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

sodium picosulfate

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

InChI

1S/C18H15NO8S2.2Na/c20-28(21,22)26-15-8-4-13(5-9-15)18(17-3-1-2-12-19-17)14-6-10-16(11-7-14)27-29(23,24)25;;/h1-12,18H,(H,20,21,22)(H,23,24,25);;/q;2*+1/p-2

InChI key

GOZDTZWAMGHLDY-UHFFFAOYSA-L

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Picosulfate for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Jennifer A Flemming et al.
Gastrointestinal endoscopy, 75(3), 537-544 (2011-12-24)
Picosulfate, magnesium oxide, and citric acid solution is a small-volume agent for colon cleansing before colonoscopy that is extremely well tolerated by patients, safe, and efficacious. Studies of other cleansing agents have suggested that split-dose regimens may further enhance efficacy.
G Manes et al.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 15(9), 1145-1153 (2013-04-16)
The study compared the efficacy, safety and tolerability of a low-volume picosulphate/magnesium citrate preparation with that of polyethylene glycol plus ascorbic acid (PEG + ASC) in a randomized clinical trial (RCT). A multicentre randomized, single-blinded study was designed. Adult outpatients
Annie O O Chan
Hong Kong medical journal = Xianggang yi xue za zhi, 18(5), 388-394 (2012-09-29)
OBJECTIVES. Although Picolax (sodium picosulphate and magnesium citrate) has been widely documented for use in bowel preparation, there is limited literature on its efficacy in the treatment of constipation. Refractory constipation is a more difficult situation with limited treatment options
Drug eruption due to sodium picosulfate.
Asuka Ishikawa et al.
European journal of dermatology : EJD, 22(3), 410-411 (2012-03-13)
Douglas K Rex et al.
Gastrointestinal endoscopy, 78(1), 132-141 (2013-04-10)
New bowel cleansers for colonoscopy that lead to improved efficacy, safety, and tolerability are needed. This study evaluated a nonphosphate, dual-action, low-volume, orange-flavored preparation containing sodium picosulfate and magnesium citrate (P/MC). Multicenter, assessor-blinded, randomized, noninferiority study. University hospitals, academic medical

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