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Y0001092

峰鉴别用氢化可的松

Name: 峰鉴别用氢化可的松
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

氢化可的松, 11β,17α,21-三羟基孕酮-4-烯-3,20-二酮, 17-羟基皮质酮标准液, 4-孕烯-11β,17α,21-三醇-3,20-二酮, 皮质醇标准液, 肯德尔氏化合物F, 赖希斯坦氏物质M

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About This Item

经验公式（希尔记法）:

C₂₁H₃₀O₅

CAS号:

50-23-7

分子量:

362.46

Beilstein:

1354819

MDL编号:

MFCD00011654

UNSPSC代码:

41116107

PubChem化学物质编号:

329831259

NACRES:

NA.24

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H1400000

醋酸氢化可的松

Y0001482

峰鉴别用醋酸氢化可的松

Supelco

PHR2158

Hydrocortisone Impurity F

Supelco

PHR1014

氢化可的松

Supelco

25539

乙酸己酯

Sigma-Aldrich

SML3747

IM1761092 hydrochloride

Supelco

94954

L -肉碱盐酸盐

USP

1250008

雌二醇

Sigma-Aldrich

H4001

氢化可的松

H1300000

氢化可的松

等级

pharmaceutical primary standard

API类

hydrocortisone

制造商/商品名称

EDQM

mp

211-214 °C (lit.)

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO

InChI

1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

InChI key

JYGXADMDTFJGBT-VWUMJDOOSA-N

基因信息

human ... NR3C1(2908)

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Hydrocortisone for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

生化/生理作用

肾上腺皮质分泌的原始糖皮质激素。

肾上腺皮质分泌的原始糖皮质激素。它的抗炎效力是皮质酮的三倍，但 Na²⁺ 保留效力要低得多。

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

警示用语：

Danger

危险声明

H360Df,H373

预防措施声明

P202 - P260 - P280 - P308 + P313 - P405 - P501

危险分类

Repr. 1A - STOT RE 2

靶器官

Adrenal gland,Bone marrow

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Hypercaloric diets with increased meal frequency, but not meal size, increase intrahepatic triglycerides: a randomized controlled trial.

Karin E Koopman et al.

Hepatology (Baltimore, Md.), 60(2), 545-553 (2014-03-29)

American children consume up to 27% of calories from high-fat and high-sugar snacks. Both sugar and fat consumption have been implicated as a cause of hepatic steatosis and obesity but the effect of meal pattern is largely understudied. We hypothesized

Stress enhances reconsolidation of declarative memory.

Marieke G N Bos et al.

Psychoneuroendocrinology, 46, 102-113 (2014-06-03)

Retrieval of negative emotional memories is often accompanied by the experience of stress. Upon retrieval, a memory trace can temporarily return into a labile state, where it is vulnerable to change. An unresolved question is whether post-retrieval stress may affect

Efficacy of hydrocortisone in preventing posttraumatic stress disorder following critical illness and major surgery.

Gustav Schelling et al.

Annals of the New York Academy of Sciences, 1071, 46-53 (2006-08-08)

Like other humans exposed to extreme trauma, patients who have been treated in an intensive care unit (ICU) often report traumatic memories. Extremely traumatic memories from the ICU in some of these patients are associated with the development of posttraumatic

GLP-1 receptor activation modulates appetite- and reward-related brain areas in humans.

Liselotte van Bloemendaal et al.

Diabetes, 63(12), 4186-4196 (2014-07-30)

Gut-derived hormones, such as GLP-1, have been proposed to relay information to the brain to regulate appetite. GLP-1 receptor agonists, currently used for the treatment of type 2 diabetes (T2DM), improve glycemic control and stimulate satiety, leading to decreases in

Postnatal hydrocortisone treatment for chronic lung disease in the preterm newborn and long-term neurodevelopmental follow-up.

K J Rademaker et al.

Archives of disease in childhood. Fetal and neonatal edition, 93(1), F58-F63 (2007-09-13)

The benefits versus the risks of postnatal administration of steroids in preterm-born infants are still debatable. This review examines the literature on postnatal hydrocortisone treatment for chronic lung disease (CLD) in preterm-born infants with a particular focus on the effects

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主要文件

安全信息

峰鉴别用氢化可的松

European Pharmacopoeia (EP) Reference Standard

About This Item

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属性

等级

API类

制造商/商品名称

mp

应用

包装形式

储存温度

SMILES字符串

InChI

InChI key

基因信息

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说明

一般描述

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生化/生理作用

包装

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警示用语：

危险声明

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储存分类代码

WGK

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闪点(°C)

法规信息

文件

分析证书(COA)

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