InChI key
CTKINSOISVBQLD-UHFFFAOYSA-N
SMILES string
OCC1CO1
InChI
1S/C3H6O2/c4-1-3-2-5-3/h3-4H,1-2H2
grade
pharmaceutical primary standard
vapor density
2.15 (vs air)
vapor pressure
0.9 mmHg ( 25 °C)
API family
levodropropizine
autoignition temp.
780 °F
manufacturer/tradename
EDQM
refractive index
n20/D 1.433 (lit.)
bp
61-62 °C/15 mmHg (lit.)
density
1.117 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
−20°C
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Levodropropizine impurity C EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
signalword
Danger
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
161.6 °F
flash_point_c
72 °C
Glycidol.
IARC monographs on the evaluation of carcinogenic risks to humans, 77, 469-486 (2000-12-02)
Hirotoshi Akane et al.
Journal of applied toxicology : JAT, 34(12), 1389-1399 (2014-01-08)
We previously found that exposure to glycidol at 1000 ppm in drinking water caused axonopathy in maternal rats and aberrations in late-stage hippocampal neurogenesis, targeting the process of neurite extension in offspring. To identify the profile of developmental neurotoxicity of
Hirotoshi Akane et al.
Toxicology and applied pharmacology, 279(2), 150-162 (2014-06-11)
We previously found that the 28-day oral toxicity study of glycidol at 200mg/kg/day in rats resulted in axonopathy in both the central and peripheral nervous systems and aberrations in the late-stage of hippocampal neurogenesis targeting the process of neurite extension.
Nadiya Bakhiya et al.
Molecular nutrition & food research, 55(4), 509-521 (2011-02-26)
Fatty acid esters of 3-chloropropane-1,2-diol (3-MCPD) and glycidol are a newly identified class of food process contaminants. They are widespread in refined vegetable oils and fats and have been detected in vegetable fat-containing products, including infant formulas. There are no
B D Craft et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 30(1), 46-51 (2012-10-02)
Recently, fatty acid esters of monochloropropanediol (MCPD) and that of glycidol have been reported in refined edible oils. Since then a wealth of research has been published on the factors influencing the formation of these contaminants in foods. It can
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