等级
pharmaceutical primary standard
API类
nicotine
制造商/商品名称
EDQM
应用
pharmaceutical (small molecule)
格式
neat
储存温度
−20°C
SMILES字符串
CN1CCC[C@H]1C2=CC=CN=C2.C
InChI
1S/C10H14N2.CH4/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;/h2,4,6,8,10H,3,5,7H2,1H3;1H4/t10-;/m0./s1
InChI key
RYYKFQGHMYGLEL-PPHPATTJSA-N
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Nicotine for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
生化/生理作用
原型烟酸乙酰胆碱受体激动剂;天然异构体。
包装
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他说明
Sales restrictions may apply.
相关产品
产品编号
说明
价格
警示用语：
Danger
危险分类
Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2
WGK
WGK 2
闪点(°F)
289.8 °F
闪点(°C)
143.2 °C
法规信息
监管及禁止进口产品
June Bryan de la Peña et al.
Behavioural brain research, 272, 156-164 (2014-07-06)
Nicotine/cigarette addiction starts young. Indeed, most smokers started when they were adolescents. Adolescence has been implicated to be a critical period for nicotine/cigarette addiction, thus it is important to understand the consequences of such early exposure. In the present study
Matthew L Banks
Experimental and clinical psychopharmacology, 22(3), 266-273 (2014-02-20)
Preclinical drug discrimination procedures have been useful in understanding the pharmacological mechanisms of the subjective-like effects of abused drugs. Converging lines of evidence from neurochemical and behavioral studies implicate a potential role of nicotinic acetylcholine (nACh) receptors in the abuse-related
Yuan-yuan Zhang et al.
Acta pharmacologica Sinica, 35(9), 1137-1149 (2014-08-05)
The non-neuronal acetylcholine system (NNAS) in endothelial cells participates in modulating endothelial function, vascular tone, angiogenesis and inflammation, thus plays a critical role in cardiovascular diseases. In this study, we used a proteomic approach to study potential downstream receptor-effectors of
Raphaël Eddine et al.
Scientific reports, 5, 8184-8184 (2015-02-03)
Midbrain dopamine (DA) neurons are key players in motivation and reward processing. Increased DA release is thought to be central in the initiation of drug addiction. Whereas dopamine neurons are generally considered to be activated by drugs such as nicotine
P P Muldoon et al.
British journal of pharmacology, 172(3), 869-882 (2014-09-27)
Abrupt discontinuation of nicotine, the main psychoactive component in tobacco, induces a withdrawal syndrome in nicotine-dependent animals, consisting of somatic and affective signs, avoidance of which contributes to drug maintenance. While blockade of fatty acid amide hydrolase, the primary catabolic
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