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主要文件

Y0000737

黄酮哌酯杂质A

European Pharmacopoeia (EP) Reference Standard

别名:

3-Methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylic acid

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About This Item

经验公式(希尔记法):
C17H12O4
CAS号:
分子量:
280.27
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

flavoxate

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

O1c2c(cccc2C(=O)O)C(=O)C(=C1c3ccccc3)C

InChI

1S/C17H12O4/c1-10-14(18)12-8-5-9-13(17(19)20)16(12)21-15(10)11-6-3-2-4-7-11/h2-9H,1H3,(H,19,20)

InChI key

KMMBBZOSQNLLMN-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Flavoxate impurity A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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C X Zhang et al.
Journal of chromatography, 612(2), 287-294 (1993-02-26)
The effects of tetraalkylammonium salts and sodium dodecyl sulphate on the migration behaviour of human urinary components and other negatively charged or neutral solutes were investigated. The sulphate acted mainly on hydrophobic and positively charged substances, whereas the ammonium salts
M Caine et al.
Urology, 37(4), 390-394 (1991-04-01)
The antispasmodic effects of the flavone compounds flavoxate hydrochloride, 3-methylflavone carboxylic acid (MFCA), and REC 15/2053 (and in the case of the detrusor, oxybutynin), on the human detrusor, prostatic adenoma, prostatic capsule, and bladder neck, were studied by the in
M T Sheu et al.
Journal of chromatography. B, Biomedical sciences and applications, 751(1), 79-86 (2001-03-10)
An improved HPLC method was developed for the concentration determination of the metabolite of flavoxate, 3-methyl-flavone-8-carboxylic acid (MFCA), in plasma in an attempt to compare two flavoxate tablet formulations. This HPLC method was validated by examining the precision and the
P Cazzulani et al.
Arzneimittel-Forschung, 38(3), 379-382 (1988-03-01)
The pharmacological properties of 3-methylflavone-8-carboxylic acid (MFCA), the main metabolite of flavoxate, have been studied in vitro and in vivo. MFCA did not display antispasmodic activity on isolated organs contractions induced by histamine, acetylcholine or CaCl2, nor did it exhibit
Alaa el-Gindy et al.
Drug development and industrial pharmacy, 34(12), 1311-1322 (2008-10-14)
Liquid chromatographic method was presented for the determination of flavoxate hydrochloride (FX) and its hydrolysis product. The method was based on high-performance liquid chromatographic (HPLC) separation of FX from its hydrolysis product on CN column using a mobile phase consisting

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