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Merck
CN

Y0000684

甲氧苄啶

European Pharmacopoeia (EP) Reference Standard

别名:

2,4-二氨基-5-(3,4,5-三甲氧基苄基)嘧啶, NSC 106568

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About This Item

经验公式(希尔记法):
C14H18N4O3
CAS号:
分子量:
290.32
Beilstein:
625127
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

trimethoprim

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC

InChI

1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18)

InChI key

IEDVJHCEMCRBQM-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

主要作为抗细菌剂。 二氢叶酸还原酶抑制活性和原核酶选择性。

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

象形图

Health hazardExclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral - Repr. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Khalid Tai et al.
PloS one, 7(9), e46269-e46269 (2012-10-03)
Regulating transgene expression in vivo by delivering oral drugs has been a long-time goal for the gene therapy field. A novel gene regulating system based on targeted proteasomal degradation has been recently developed. The system is based on a destabilizing
Ivan Senta et al.
Water research, 47(2), 705-714 (2012-11-29)
Comprehensive study on the occurrence and fate of several classes of antimicrobials, including sulfonamides, trimethoprim, fluoroquinolones and macrolides, in Croatian municipal wastewaters was performed using an integrated approach, which comprised analysis of both dissolved and particulate fractions. A nation-wide screening
Hai Liu et al.
Journal of hazardous materials, 235-236, 367-375 (2012-08-25)
The preparation of activated carbons (AC-H(x)P(y)O(z)) by four kinds of oxyacids of phosphorus (H(3)PO(4), H(4)P(2)O(7), HPO(3) and H(3)PO(3)) activation of lotus stalk (LS) was studied, with a particular focus on the effect of these H(x)P(y)O(z) on both surface chemistry and
Kyuho Han et al.
Nature methods, 11(1), 86-93 (2013-11-12)
Protein concentrations are often regulated by dynamic changes in translation rates. Nevertheless, it has been challenging to directly monitor changes in translation in living cells. We have developed a reporter system to measure real-time changes of translation rates in human
J T Andersen et al.
Epidemiology and infection, 141(8), 1749-1755 (2012-09-27)
The antibiotic trimethoprim acts as a folate antagonist. Since trophoblasts are very sensitive to drugs that interfere with the folic acid cycle and thereby inhibit DNA synthesis, use of trimethoprim during the first trimester could be associated with miscarriage. A

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