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Merck
CN

Y0000577

系统适用性试验用泮库溴铵

European Pharmacopoeia (EP) Reference Standard

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别名:
泮库溴铵, 1,1′-[(2β,3α,5α,16β,17β)-3,17-双(乙酰氧基)雄甾烷-2,16-二基]双(1-甲基哌啶鎓)二溴化物
经验公式(希尔记法):
C35H60Br2N2O4
CAS号:
分子量:
732.67
Beilstein:
4226892
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

pancuronium 

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES字符串

[Br-].[Br-].[H][C@@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@@H](OC(C)=O)[C@H](C[C@@]34[H])[N+]5(C)CCCCC5)[C@@]1(C)C[C@@H]([C@H](C2)OC(C)=O)[N+]6(C)CCCCC6

InChI

1S/C35H60N2O4.2BrH/c1-24(38)40-32-21-26-13-14-27-28(35(26,4)23-31(32)37(6)19-11-8-12-20-37)15-16-34(3)29(27)22-30(33(34)41-25(2)39)36(5)17-9-7-10-18-36;;/h26-33H,7-23H2,1-6H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1

InChI key

NPIJXCQZLFKBMV-YTGGZNJNSA-L

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Pancuronium bromide for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

象形图

Skull and crossbones

警示用语:

Danger

危险声明

预防措施声明

危险分类

Acute Tox. 3 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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M F Roizen et al.
Annals of internal medicine, 88(1), 64-68 (1978-01-01)
Pancuronium bromide is a nondepolarizing muscle relaxant approved to induce skeletal muscle relaxation during anesthesia and to facilitate the management of patients undergoing mechanical ventilation. The use of pancuronium bromide during surgery led to the appreciation that it has advantages
J Simoes et al.
Journal of perinatology : official journal of the California Perinatal Association, 9(2), 215-218 (1989-06-01)
Nursing care of the newborn in respiratory distress has become highly sophisticated and technical, requiring skill in principles of neonatal assessment and therapeutic interventions. It is important to be knowledgeable about the technical aspects of the equipment and monitors. However
Alina Teliban et al.
Journal of neurophysiology, 111(10), 2071-2083 (2014-02-28)
Intact and injured cutaneous C-fibers in the rat sural nerve are cold sensitive, heat sensitive, and/or mechanosensitive. Cold-sensitive fibers are either low-threshold type 1 cold sensitive or high-threshold type 2 cold sensitive. The hypothesis was tested, in intact and injured
Pancuronium bromide: a review of its pharmacological properties and clinical application.
T M Speight et al.
Drugs, 4(3), 163-226 (1972-01-01)
F Bolzoni et al.
The Journal of physiology, 593(4), 947-966 (2014-11-25)
Trans-spinal DC stimulation affects both postsynaptic neurons and the presynaptic axons providing input to these neurons. In the present study, we show that intraspinally applied cathodal current replicates the effects of trans-spinal direct current stimulation in deeply anaesthetized animals and

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