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Merck
CN

Y0000572

羟乙膦酸钠 二钠

European Pharmacopoeia (EP) Reference Standard

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别名:
1-Hydroxyethane-1,1-bisphosphonic acid disodium salt
经验公式(希尔记法):
C2H6Na2O7P2
CAS号:
分子量:
249.99
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

etidronate

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

InChI

1S/C2H8O7P2.2Na/c1-2(3,10(4,5)6)11(7,8)9;;/h3H,1H3,(H2,4,5,6)(H2,7,8,9);;/q;2*+1/p-2

InChI key

GWBBVOVXJZATQQ-UHFFFAOYSA-L

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Etidronate disodium EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

象形图

Exclamation mark

警示用语:

Warning

危险声明

预防措施声明

危险分类

Acute Tox. 4 Oral

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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Determination of etidronate disodium tablets by ion chromatography with indirect UV detection.
Tsai E W, et al.
Journal of Pharmaceutical and Biomedical Analysis, 11(6), 513-516 (1993)
S M Krane
Annals of internal medicine, 96(5), 619-625 (1982-05-01)
Control of Paget's disease of bone has been possible through treatment with agents that decrease bone resorption; calcitonins, diphosphonates, and mithramycin. The pagetic lesion is not, however, cured. Etidronate disodium is one of the diphosphonates. The clinical improvement attained with
The role of risedronate in osteopenia in Crohn's disease.
Alice Buchan et al.
Gut, 64(1), 185-185 (2013-12-07)
Ivana Sestak et al.
The Lancet. Oncology, 15(13), 1460-1468 (2014-12-03)
Aromatase inhibitors prevent breast cancer in postmenopausal women at high risk of the disease but are associated with accelerated bone loss. We assessed effectiveness of oral risedronate for prevention of reduction in bone mineral density (BMD) after 3 years of
Jörg Schilcher et al.
Acta orthopaedica, 86(1), 100-107 (2015-01-15)
Use of bisphosphonates in women is associated with higher risk of atypical femoral fractures. The risk in terms of timing of use and type of bisphosphonate, and in men, remains unclear. We reviewed radiographs of 5,342 Swedish women and men

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