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Merck
CN

Y0000487

来氟米特杂质A

European Pharmacopoeia (EP) Reference Standard

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别名:
4-(三氟甲基)苯胺, α,α,α-三氟对甲苯胺, 4-氨基三氟甲苯
线性分子式:
CF3C6H4NH2
CAS号:
分子量:
161.12
Beilstein:
1564853
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

leflunomide

制造商/商品名称

EDQM

折射率

n20/D 1.483 (lit.)

bp

83 °C/12 mmHg (lit.)

密度

1.283 g/mL at 25 °C (lit.)

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

Nc1ccc(cc1)C(F)(F)F

InChI

1S/C7H6F3N/c8-7(9,10)5-1-3-6(11)4-2-5/h1-4H,11H2

InChI key

ODGIMMLDVSWADK-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Leflunomide impurity A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

WGK

WGK 3


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R E Cilley et al.
Journal of pediatric surgery, 35(1), 113-118 (2000-01-26)
The mechanisms by which static airway pressures in the developing lung affect development are unknown. The in vitro murine fetal lung model with airway ligation reproduces the phenomenon of intraluminal airway pressure in developing lungs. We have applied the technique
V Kruft et al.
Biochimie, 73(7-8), 855-860 (1991-07-01)
The complete amino acid sequences of 3 proteins from the 50S subunit of Bacillus stearothermophilus ribosomes were determined by N-terminal sequence analysis and by sequencing of overlapping fragments obtained from enzymatic digestions and chemical cleavages. The proteins BstL28, BstL33 and
B A Maguire et al.
Molecular microbiology, 23(2), 237-245 (1997-01-01)
Strain BM108 of Escherichia coli has a chromosomal mutation in the rpmB,G operon that prevents synthesis of ribosomal proteins L28 and L33. The mutation was lethal unless synthesis of protein L28 was induced from a plasmid. Without protein L28, RNA
H Klein
Biochemistry and cell biology = Biochimie et biologie cellulaire, 75(2), 177-182 (1997-01-01)
A cDNA coding for the hamster S24 ribosomal protein was used to isolate homologous genes from a Syrian hamster fibroblast genomic library. Southern analysis, using S24 ribosomal protein cDNA and two probes derived from the 5' and 3' ends, suggests
J Seifert et al.
Toxicology, 83(1-3), 49-59 (1993-10-25)
Reactive isomeric 3- and 4-trifluoromethylanilines (3-,4-TFMA), and control aniline itself, induced the following effects on biosynthesis of DNA in the liver, kidney, thymus and spleen of rats: (a) The administration of 4-TFMA initially suppressed the utilization of labeled thymidine for

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