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安全信息

安全和法规

Y0000452

硫酸吗啡

Name: 硫酸吗啡
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

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别名:

吗啡硫酸盐五水合物, 吗啡五水硫酸盐

经验公式（希尔记法）:

C₃₄H₄₀N₂O₁₀S · 5H₂O

CAS号:

6211-15-0

分子量:

758.83

MDL编号:

MFCD00150902

UNSPSC代码:

12352210

PubChem化学物质编号:

329830964

NACRES:

NA.24

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Sigma-Aldrich

M8777

吗啡硫酸盐五水合物

USP

1448005

吗啡硫酸盐五水合物

Supelco

Y0000830

吗啡硫酸盐五水合物

Y0000451

吗啡盐酸盐三水合物

BP648

硫酸吗啡

Supelco

M3402

吗啡-d₃ 盐酸盐三水合物

Y0001471

吗啡硫酸盐五水合物

Y0000095

地奥司明

Supelco

PHR8831

海洛因盐酸盐

BP683

哌替啶盐酸盐

等级

pharmaceutical primary standard

API类

morphine

制造商/商品名称

EDQM

药品控制

regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES字符串

O.O.O.O.O.OS(O)(=O)=O.CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4O)c35.CN6CC[C@]78[C@H]9Oc%10c(O)ccc(C[C@@H]6[C@@H]7C=C[C@@H]9O)c8%10

InChI

1S/2C17H19NO3.H2O4S.5H2O/c2*1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18;1-5(2,3)4;;;;;/h2*2-5,10-11,13,16,19-20H,6-8H2,1H3;(H2,1,2,3,4);5*1H2/t2*10-,11+,13-,16-,17-;;;;;;/m00....../s1

InChI key

GRVOTVYEFDAHCL-RTSZDRIGSA-N

基因信息

human ... OPRM1(4988)

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Morphine sulfate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

警示用语：

Warning

危险声明

H302,H336

预防措施声明

P301 + P312 + P330

危险分类

Acute Tox. 4 Oral - STOT SE 3

靶器官

Central nervous system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

分析证书(COA)

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Dose-dependent effects of morphine on lipopolysaccharide (LPS)-induced inflammation, and involvement of multixenobiotic resistance (MXR) transporters in LPS efflux in teleost fish.

Hélène Mottaz et al.

Environmental pollution (Barking, Essex : 1987), 221, 105-115 (2016-12-25)

Opioid drugs, such as morphine (MO), detected in aquatic environments worldwide, may harm fish due to their semi-persistence and ability to potently interact with molecular targets conserved across vertebrates. Here, we established a waterborne bacterial lipopolysaccharide (LPS) challenge assay with

MeCP2 repression of G9a in regulation of pain and morphine reward.

Zhi Zhang et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(27), 9076-9087 (2014-07-06)

Opioids are commonly used for pain relief, but their strong rewarding effects drive opioid misuse and abuse. How pain affects the liability of opioid abuse is unknown at present. In this study, we identified an epigenetic regulating cascade activated by

Serotonin, morphine, and neuropathic pain: not a simple story.

Kelly Byrne et al.

Anesthesiology, 121(2), 217-218 (2014-06-03)

Identification of a novel spinal dorsal horn astroglial D-amino acid oxidase-hydrogen peroxide pathway involved in morphine antinociceptive tolerance.

Nian Gong et al.

Anesthesiology, 120(4), 962-975 (2013-08-10)

D-Amino acid oxidase (DAAO) is a flavin adenine dinucleotide-dependent peroxisomal flavoenzyme which is almost exclusively expressed within astrocytes in the spinal cord. DAAO catalyzes oxidation of D-amino acids to hydrogen peroxide, which is a stable and less active reactive oxygen

Single-shot intraoperative local anaesthetic infiltration does not reduce morphine consumption after total hip arthroplasty: a double-blinded placebo-controlled randomized study.

L Zoric et al.

British journal of anaesthesia, 112(4), 722-728 (2014-01-17)

The infiltration of local anaesthetic (LA), ketorolac, and epinephrine has been suggested to be effective for analgesia after total hip arthroplasty (THA). The part of action of each component of the mixture remains unclear. We investigated the contribution of infiltration

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硫酸吗啡

European Pharmacopoeia (EP) Reference Standard

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格式

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SMILES字符串

InChI

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说明

一般描述

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包装

其他说明

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警示用语：

危险声明

预防措施声明

危险分类

靶器官

WGK

闪点(°F)

闪点(°C)

法规信息

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