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Merck
CN

Y0000384

生育酚醋酸酯

European Pharmacopoeia (EP) Reference Standard

别名:

DL-α-生育酚乙酸酯, 生育酚乙酸酯, 维生素 E 醋酸酯

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About This Item

经验公式(希尔记法):
C31H52O3
CAS号:
分子量:
472.74
Beilstein:
97512
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

生物来源

synthetic

等级

pharmaceutical primary standard

Agency

EP

API类

tocopherol

形式

solid

制造商/商品名称

EDQM

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

密度

0.96 g/mL at 20 °C (lit.)

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES字符串

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1

InChI

1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1

InChI key

ZAKOWWREFLAJOT-CEFNRUSXSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
All-rac-alpha-tocopheryl acetate, the ester of all-rac-alpha-tocopherol, is a commercial form of vitamin E. It is responsible for the protection of phenol groups of the parent tocopherol against oxidation.

应用

All-rac-alpha-tocopheryl acetate for peak identification may be used as an EP reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

WGK

WGK 1

闪点(°F)

No data available

闪点(°C)

No data available


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分析证书(COA)

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all-rac-?-Tocopheryl acetate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 129(7), 3802-3804 (2011)
All-rac-alpha-tocopherol acetate is a better vitamin E source than all-rac-alpha-tocopherol succinate for broilers
Jensen S, et al.
The Journal of Nutrition, 129(7), 1355-1360 (1999)
Succinic Acids?Advances in Research and Application: 2013 Edition: ScholarlyBrief
Acton QA
Succinic Acids?Advances in Research and Application (2013)
Po-Hsien Huang et al.
Science signaling, 6(267), ra19-ra19 (2013-03-21)
Vitamin E is a fat-soluble vitamin with antioxidant properties. Tocopherols are the predominant form of vitamin E found in the diet and in supplements and have garnered interest for their potential cancer therapeutic and preventive effects, such as the dephosphorylation
Katharina M Espe et al.
Clinical journal of the American Society of Nephrology : CJASN, 8(3), 452-458 (2013-01-22)
Trials with the antioxidant vitamin E have failed to show benefit in the general population. Considering the different causes of death in ESRD, this study investigated the association between plasma concentrations of α-tocopherol and specific clinical outcomes in diabetic hemodialysis

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