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Merck
CN

Y0000362

Ciprofibrate

European Pharmacopoeia (EP) Reference Standard

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别名:
2-[p-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
经验公式(希尔记法):
C13H14Cl2O3
CAS号:
分子量:
289.15
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

ciprofibrate

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES字符串

CC(C)(Oc1ccc(cc1)C2CC2(Cl)Cl)C(O)=O

InChI

1S/C13H14Cl2O3/c1-12(2,11(16)17)18-9-5-3-8(4-6-9)10-7-13(10,14)15/h3-6,10H,7H2,1-2H3,(H,16,17)

InChI key

KPSRODZRAIWAKH-UHFFFAOYSA-N

基因信息

human ... PPARA(5465)

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Ciprofibrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

象形图

Health hazard

警示用语:

Danger

危险声明

预防措施声明

危险分类

Carc. 1B

WGK

WGK 3


分析证书(COA)

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M J Chapman et al.
Atherosclerosis, 124 Suppl, S21-S28 (1996-07-01)
Triglyceride levels greater than 150 mg/dl are associated with the atherogenic lipoprotein phenotype, represented by a predominance of small, dense low density lipoproteins (LDL) and diminished concentrations of high density lipoproteins. This phenotype is characteristic of patients with combined hyperlipidemia
G Turpin et al.
Atherosclerosis, 124 Suppl, S83-S87 (1996-07-01)
Ciprofibrate is an effective treatment for three main types of atherogenic hyperlipoproteinaemia: type IIa hypercholesterolaemia, type IIb combined hyperlipidaemia, and type IV hypertriglyceridaemia. In type IIa hypercholesterolaemia, administration of 100 mg/day of ciprofibrate, to approximately 3000 patients, decreased total cholesterol
D J Betteridge
Postgraduate medical journal, 69 Suppl 1, S42-S47 (1993-01-01)
The cornerstone of management in hyperlipidaemia is dietary and lifestyle therapy. Nonetheless, a proportion of patients will require drug therapy. Of the currently available choices, statins are of obvious value for raised cholesterol and low dose resins have a place

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