推荐产品
等级
pharmaceutical primary standard
API类
roxithromycin
制造商/商品名称
EDQM
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)C(=N/OCOCCOC)\C(C)C(O)C1(C)O
InChI
1S/C41H76N2O15/c1-15-29-41(10,49)34(45)24(4)31(42-53-21-52-17-16-50-13)22(2)19-39(8,48)36(58-38-32(44)28(43(11)12)18-23(3)54-38)25(5)33(26(6)37(47)56-29)57-30-20-40(9,51-14)35(46)27(7)55-30/h22-30,32-36,38,44-46,48-49H,15-21H2,1-14H3/b42-31+
InChI key
RXZBMPWDPOLZGW-FEMONOMJSA-N
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Roxithromycin for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
生化/生理作用
Semisynthetic erythromycin derivative. Impairs NADPH oxidase activation and alters translocation of its cytosolic components to the neutrophil membrane.
包装
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他说明
Sales restrictions may apply.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
J Gaillat
Presse medicale (Paris, France : 1983), 26 Suppl 2, 16-21 (1997-03-01)
BRONCHIAL SUPERINFECTIONS: Macrolides are first-line antibiotics for acute bronchitis and infectious complications of chronic bronchitis. Data in the literature on roxithromycin treatment in respiratory tract infections demonstrate to clinical and bacteriological efficacy at high doses comparable with other available antibiotics.
C Mayaud
Presse medicale (Paris, France : 1983), 26 Suppl 2, 27-29 (1997-03-01)
A LOGICAL HYPOTHESIS: Recent publications raise the question of an association between Chlamydia pneumoniae and asthma. There has been no formal proof justifying routine search for C.pneumoniae in patients with uncontrolled asthma nor for systematic treatment with an antibiotic. Can
[Bacillary angiomatosis in HIV infection. Update apropos of a case treated with roxithromycin].
M Duong et al.
Annales de medecine interne, 143(2), 107-109 (1992-01-01)
[Roxithromycin (Forilin, Surlid)].
N H Eriksen et al.
Ugeskrift for laeger, 152(6), 411-412 (1990-02-05)
A Markham et al.
Drugs, 48(2), 297-326 (1994-08-01)
Roxithromycin is a derivative of the macrolide antibacterial erythromycin with in vitro antibacterial activity resembling that of the parent compound. The drug has activity against some Staphylococcus spp., many Streptococcus spp., Moraxella (Branhamella) catarrhalis, Mycoplasma pneumoniae, Legionella pneumophila and Chlamydia
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