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Y0000053

17α-Dihydroequilin

European Pharmacopoeia (EP) Reference Standard

别名:

α-Equilol, Estra-1,3,5(10),7-tetraene-3,17α-diol

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About This Item

经验公式(希尔记法):
C18H22O2
CAS号:
分子量:
270.37
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

equilin

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

−20°C

SMILES字符串

OC1C2(C(CC1)C3=CCc4c(ccc(c4)O)C3CC2)C

InChI

1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3-5,10,14,16-17,19-20H,2,6-9H2,1H3

InChI key

NLLMJANWPUQQTA-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

17α-Dihydroequilin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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B R Bhavnani et al.
The Journal of clinical endocrinology and metabolism, 77(5), 1269-1274 (1993-11-01)
The constant infusion of [3H]equilin sulfate ([3H]EqS) was used to estimate the MCR of equilin sulfate (EqS) and to measure the conversion of this estrogen to equilin (Eq), equilenin (Eqn), equilenin sulfate (EqnS), 17 beta-dihydroequilin (17 beta-Eq), 17 beta-dihydroequilin sulfate
B R Bhavnani et al.
Journal of the Society for Gynecologic Investigation, 7(3), 175-183 (2000-06-24)
To compare the pharmacokinetics and relative bioavailabilities of key estrogen components of Premarin (Wyeth-Ayerst, Canada) with those of a generic conjugated estrogen preparation, C.E.S. (synthetic mixture of estrogens; ICN, Montreal, Canada) in healthy postmenopausal women. We conducted a randomized, single-dose
E Arteaga et al.
Climacteric : the journal of the International Menopause Society, 1(4), 284-289 (2002-03-23)
To determine the relative bioavailability of the estrogenic components of a generic brand of conjugated estrogens marketed in Chile in comparison to that of Conpremin (Premarin in the United States). A randomized cross-over study was conducted on 16 healthy postmenopausal
S A Washburn et al.
American journal of obstetrics and gynecology, 169(2 Pt 1), 251-254 (1993-08-01)
Our purpose was to determine the effect of Premarin (conjugated estrogens) and three of its component estrogens on uterine weight and plasma cholesterol concentrations in surgically menopausal female rats. A randomized trial of Premarin and three component estrogens--estrone sulfate, 17
B R Bhavnani et al.
The Journal of clinical endocrinology and metabolism, 78(1), 197-204 (1994-01-01)
The MCRs of 17 beta-dihydroequilin sulfate and 17 beta-dihydroequilin were determined in normal postmenopausal women by single iv injection of either 17 beta-[3H]dihydroequilin sulfate ([3H]17 beta-EqS) or 17 beta-[3H]dihydroequilin ([3H]17 beta-Eq). After the administration of [3H]17 beta-EqS, blood was drawn

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