推荐产品
等级
analytical standard
质量水平
方案
≥90%
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
[Na+].COc1cc(c(cc1-n2nc(n[n+]2-c3cc(c(cc3OC)[N+]([O-])=O)S([O-])(=O)=O)C(=O)Nc4ccccc4)S([O-])(=O)=O)[N+]([O-])=O
InChI
1S/C22H17N7O13S2.Na/c1-41-17-8-15(28(31)32)19(43(35,36)37)10-13(17)26-24-21(22(30)23-12-6-4-3-5-7-12)25-27(26)14-11-20(44(38,39)40)16(29(33)34)9-18(14)42-2;/h3-11H,1-2H3,(H2-,23,30,35,36,37,38,39,40);/q;+1/p-1
InChI key
JACYMBNQPPWQML-UHFFFAOYSA-M
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应用
可用于艾滋病和癌症检测。
有关合适的仪器技术的更多信息,请参阅产品′的分析证书。联系技术服务部以获得进一步支持。
XTT可与吩嗪硫酸甲酯(PMS)联合使用,用于筛选人肿瘤细胞系。 四唑染料也被用于真菌细胞损伤研究 、葡萄球菌的抗菌敏感性测试,以及念珠菌生物膜研究。XTT检测法的局限性也有报道。
原理
在活细胞中,XTT被代谢还原,生成可比色的水溶性甲臜产物。
警示用语:
Danger
危险声明
危险分类
Self-react. C
补充剂危害
储存分类代码
4.1A - Other explosive hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Journal of Heterocyclic Chemistry, 25, 911-911 (1988)
Cancer research, 48(17), 4827-4833 (1988-09-01)
We have previously described the application of an automated microculture tetrazolium assay (MTA) involving dimethyl sulfoxide solubilization of cellular-generated 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT)-formazan to the in vitro assessment of drug effects on cell growth (M.C. Alley et al., Proc. Am. Assoc.
Brazilian dental journal, 19(4), 364-369 (2009-01-31)
2, 3-bis (2-methoxy-4-nitro-5-sulfophenyl)-5-[(phenylamino) carbonyl]-2H-tetrazolium hydroxide (XTT) reduction assay has been used to study Candida biofilm formation. However, considering that the XTT reduction assay is dependent on cell activity, its use for evaluating mature biofilms may lead to inaccuracies since biofilm
Evidence-based complementary and alternative medicine : eCAM, 2018, 9473094-9473094 (2018-10-27)
Anti-inflammatory effects of virgin olive oil (VOO) have been described recently, along with its wound healing effect. One of the main minor compounds found in VOO is squalene (SQ), which also possesses preventive effects against skin damage and anti-inflammatory properties.
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