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安全信息

V0045000

Vancomycin 盐酸盐

European Pharmacopoeia (EP) Reference Standard

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About This Item

经验公式（希尔记法）:
C66H75Cl2N9O24 · xHCl
CAS号:
1404-93-9
分子量:
1449.25 (free base basis)
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

vancomycin

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

−20°C

SMILES字符串

[Cl-].Clc1c2ccc(c1)[C@H]([C@@H]3NC(=O)[C@H](NC(=O)[C@@H]6NC(=O)[C@@H](NC(=O)[C@@H]([C@@H](c7cc(c(cc7)Oc8c(c(cc6c8)O2)O[C@@H]9O[C@@H]([C@H]([C@@H]([C@H]9O[C@@H]%10O[C@H]([C@H]([C@](C%10)(N)C)O)C)O)O)CO)Cl)O)NC(=O)[C@H]([N+H2]C)CC(C)C)CC(=O)N)c4cc(c(cc4)O)c

InChI

1S/C66H75Cl2N9O24.ClH/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92;/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95);1H/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-;/m0./s1

InChI key

LCTORFDMHNKUSG-XTTLPDOESA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Vancomycin hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

象形图

Health hazard
GHS08

警示用语：

Danger

危险声明

H317,H334

危险分类

Resp. Sens. 1 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Joop J P Kouijzer et al.
International journal of pharmaceutics, 609, 121154-121154 (2021-10-09)
Bacterial biofilms are a huge burden on our healthcare systems worldwide. The lack of specificity in diagnostic and treatment possibilities result in difficult-to-treat and persistent infections. The aim of this in vitro study was to investigate if microbubbles targeted specifically
David W Eyre et al.
The Journal of infectious diseases, 209(9), 1446-1451 (2013-11-13)
Whole-genome sequencing was used to determine whether the reductions in recurrence of Clostridium difficile infection observed with fidaxomicin in pivotal phase 3 trials occurred by preventing relapse of the same infection, by preventing reinfection with a new strain, or by
Cheryl N Onwuchuruba et al.
American journal of obstetrics and gynecology, 210(4), 352-352 (2014-04-01)
The objective of the study was to analyze a large number of patients receiving vancomycin chemoprophylaxis and evaluate the maternal and neonatal cord blood levels at the time of delivery. Every mother who entered labor with a positive group B
Wessam Abdelhady et al.
The Journal of infectious diseases, 209(8), 1231-1240 (2014-01-10)
Staphylococcus aureus is the most common cause of endovascular infections. The staphylococcal accessory regulator A locus (sarA) is a major virulence determinant that may potentially impact methicillin-resistant S. aureus (MRSA) persistence in such infections via its influence on biofilm formation.
Christopher J Rudnisky et al.
Ophthalmology, 121(4), 835-841 (2013-12-12)
To determine the 8-year incidence of endophthalmitis after cataract surgery and to determine which surgical practices were associated with higher rates of endophthalmitis. Case-control study. A total of 75 318 eyes undergoing cataract extractions, performed by 26 different surgeons at 4 public
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