InChI key
FSSICIQKZGUEAE-UHFFFAOYSA-N
InChI
1S/C16H21N3.ClH/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15;/h3-11H,12-14H2,1-2H3;1H
SMILES string
CN(C)CCN(CC1=CC=CC=C1)C2=NC=CC=C2.Cl
grade
analytical standard
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary
format
neat
Quality Level
Gene Information
human ... HRH1(3269)
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General description
Tripelennamine hydrochloride is an antihistamine drug, which is used in the treatment of bronchitis, asthma and bronchoconstriction.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Tripelennamine hydrochloride may be used as a reference standard in the determination of tripelennamine hydrochloride in samples of animal feed by gas chromatography (GC) method, wastewater and urine using high performance liquid chromatography (HPLC) method employing fluorescence detector.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Trace determination of the antihistamines tripelennamine hydrochloride, thenyldiamine hydrochloride, and chlorothen citrate in admixture in animal feed, human urine, and wastewater by high-pressure liquid chromatography and use of a fluorescence detector.
Thompson TH, et al.
Talanta, 30(4), 251-260 (1983)
S Sekizawa et al.
Respiration physiology, 112(1), 13-22 (1998-08-08)
The response to histamine of nasal afferents has been studied in guinea pigs by recording the electrical activity of the whole ethmoidal nerve (EN) or that of single units. Guinea pigs were anaesthetized with urethane and breathed through a tracheostomy.
Y Xia et al.
European journal of pharmacology, 316(1), 81-85 (1996-11-28)
Effects of histamine and related agonists and antagonists on formation of cAMP were determined for enzymatically dissociated ganglia from the myenteric plexus of the guinea-pig small intestine. Formation of cAMP was stimulated by histamine in both dose- and time-dependent manners.
G Viola et al.
Die Pharmazie, 59(12), 948-951 (2005-01-11)
The influence of mast cell activation on the secretion of prolactin has been studied in rats receiving lysophosphatidylserine, a natural occurring phospholipid with secretagogue activity in these cells. After the i.v. injection of lysophosphatidylserine (10 mg/kg) a plasma prolactin peak
C E Johanson et al.
Experimental and clinical psychopharmacology, 6(4), 427-432 (1998-12-23)
Participants discriminated between tripelennamine and placebo in experiments differing in instructional set. In 1 experiment (SED), participants were told that 1 of the 2 drugs was more sedative-like, and during the other (STIM), 1 was more stimulant-like. During generalization tests
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