Reagent-cartridge Morpholine-2-spiro-(2-Pyr) (0)

Reagent-cartridge Morpholine-2-spiro-(2-Pyr) is a reagent cartridge for the Synple 2 Automated Synthesizer that enables the synthesis of a morpholine-pyrrolidine spirocycle from an aldehyde through the use of a SnAP reagent. The cartridge contains all necessary reagents for transforming the chosen aldehyde into a morpholine-pyrrolidine spirocycle.

Scale: up to 0.5 mmol
Heterocycle: Morpholine-pyrrolidine spirocycle
Compatible substrates: aldehyde

Cartridge contents:

• Immobilized SnAP reagent
• Cu catalyst (Cu(OTF)₂ and 2,6-lutidinium triflate)
• SCX (for purification)
• Silica (for purification)

Related Cartridges:

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• SYNPLE-H007Reagent-cartridge 3-Methylmorpholine
• SYNPLE-H011Reagent-cartridge Morpholine-2-spiro-(4-Pip)
• SYNPLE-H090Reagent-cartridge 9-OMe-Benzoxazepane
• SYNPLE-H091Reagent-cartridge 7-Br-9-OMe-Benzoxazepane

Learn more about the Synple automated synthesis platform.

Features and Benefits of Synple Platform

• Time savings - pre-installed protocols have been highly optimized, which obviates the need for the user′s own reaction development and optimization
• Easy to use - protocols are loaded by simply scanning the cartridge; does not requires any programming knowledge
• Safety - all chemicals are contained in the system, minimizing the user′s exposure
• Set-up reaction in less than 5 minutes
• Small footprint
• Plug & Play system - simple installation
• Reaction temperatures from 25 °C - 80 °C
• Cartridges available for many different reactions
• Prefilled with all required reagents
• RFID chip containing optimized reaction protocol

An integrated console for capsule-based, automated organic synthesis

For more information on heterocycle formation using SnAP reagents, visit here: SnAP Technology Spotlight

Product of Synple Chem AG