所有图片(4)
别名:
6-FP, 2-Amino-4-hydroxy-6-formylpteridine, 2-Amino-6-formylpteridin-4-one, Pterin-6-aldehyde
经验公式（希尔记法）:
C7H5N5O2
推荐产品
生物来源
synthetic
质量水平
检测方案
≥95% (HPLC)
形式
solid
环保替代产品得分
old score: 59
new score: 52
Find out more about DOZN™ Scoring
环保替代产品特性
Safer Solvents and Auxiliaries
Reduce Derivatives
Design for Degradation
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
应用
metabolomics
环保替代产品分类
储存温度
2-8°C
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相关类别
一般描述
6-Formylpterin is a Vitamin B9 (folate) metabolite and ligand to MHC class I-related protein 1 (MR1) antigens presented on mucosal-associated invariant T (MAIT) cells.
We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to the category of Re-engineered products, showing key improvements in Green Chemistry Principles “Safer Solvents and auxiliaries”, “Reduce Derivatives”, and “Design for Degradation”. Click here to view its DOZN scorecard.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Hamish E G McWilliam et al.
Trends in immunology, 38(9), 679-689 (2017-07-10)
Mucosal-associated invariant T (MAIT) cells are innate-like lymphocytes restricted by the antigen (Ag)-presenting molecule MHC class I (MHC I)-related protein 1 (MR1). The Ags presented by MR1 are vitamin B-related Ags (VitBAgs), 'building-block' metabolites of riboflavin that are synthesized by
Sidonia B G Eckle et al.
The Journal of experimental medicine, 211(8), 1585-1600 (2014-07-23)
Mucosal-associated invariant T (MAIT) cells express an invariant T cell receptor (TCR) α-chain (TRAV1-2 joined to TRAJ33, TRAJ20, or TRAJ12 in humans), which pairs with an array of TCR β-chains. MAIT TCRs can bind folate- and riboflavin-based metabolites restricted by
Lars Kjer-Nielsen et al.
Nature, 491(7426), 717-723 (2012-10-12)
Antigen-presenting molecules, encoded by the major histocompatibility complex (MHC) and CD1 family, bind peptide- and lipid-based antigens, respectively, for recognition by T cells. Mucosal-associated invariant T (MAIT) cells are an abundant population of innate-like T cells in humans that are
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