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COO原产地证书/COA分析证书

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SMB01363

5α-Tetrahydrocortisol

Name: 5α-Tetrahydrocortisol
Brand: SIAL

≥95% (HPLC)

别名:

5α-Pregnane-3α,11β,17α,21-tetrol-20-one, α-THF, 5 alpha-Tetrahydrocortisol, ATHF, Allo-3a-tetrahydrocortisol, 3α,11β,17α,21-Tetrahydroxy-5α-pregnan-20-one, 3α,5α-Tetrahydrocortisol, Allopregnane-3α,11β,17α,21-tetrol-20-one, Allotetrahydrocortisol, Kendall’s compound C, Reichstein’s substance C

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About This Item

经验公式（希尔记法）:

C₂₁H₃₄O₅

CAS号:

302-91-0

分子量:

366.49

MDL编号:

MFCD00003670

UNSPSC代码:

51111800

NACRES:

NA.21

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Sigma-Aldrich

SMB01343

Tetrahydrocortisol

Sigma-Aldrich

H4001

氢化可的松

Sigma-Aldrich

E8875

β-雌二醇

Sigma-Aldrich

SMB01373

2-Hydroxyesterone

Sigma-Aldrich

662005

U0126

Sigma-Aldrich

H0888

氢化可的松

Sigma-Aldrich

27840

肾上腺酮

Sigma-Aldrich

H5002

17α-Hydroxypregnenolone

Sigma-Aldrich

P9129

5-Pregnen-3β-ol-20-one

Sigma-Aldrich

C8667

胆固醇

质量水平

200

方案

≥95% (HPLC)

表单

solid

组成

(3α,5α)-3,11,17,21-Tetrahydroxypregnan-20-one, ≤100%

包装

pkg of 25 mg
pkg of 5 mg

颜色

white to beige

mp

244.5 °C

密度

1.205 g/cm³

储存温度

2-8°C

SMILES字符串

C[C@@]12CC[C@H](O)C[C@H]1CC[C@@H]3[C@H]4CC[C@@](O)(C(=O)CO)[C@@]4(C)C[C@@H](O)[C@@H]23

InChI

1S/C21H34O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12-16,18,22-24,26H,3-11H2,1-2H3/t12-,13+,14-,15-,16-,18+,19-,20-,21-/m0/s1

InChI key

AODPIQQILQLWGS-FDSHTENPSA-N

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一般描述

5α-Tetrahydrocortisol, also known as Allo-3a-tetrahydro cortisol (ATHC), a synthetic corticosteroid hormone derived from cortisol, is widely employed in biochemical and proteomics research. It is a metabolite of cortisol, a natural glucocorticoid that is used to treat various immune, inflammatory, and neoplastic conditions. In the context of medical diagnosis, a higher ratio of specific urinary metabolites can indicate the presence of Apparent Mineralocorticoid Excess (AME) syndrome, a rare form of hypertension linked to abnormalities in cortisol metabolism.