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文件

S7507

磺胺甲噁唑

Name: 磺胺甲噁唑
Brand: SIAL

别名:

4-氨基- N -（5-甲基-3-异恶唑基）苯磺酰胺, N ¹-（5-甲基异恶唑-3-基）磺胺

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About This Item

经验公式（希尔记法）:

C₁₀H₁₁N₃O₃S

CAS号:

723-46-6

分子量:

253.28

Beilstein:

6732984

EC 号:

211-963-3

MDL编号:

MFCD00010546

UNSPSC代码:

41116107

PubChem化学物质编号:

329824585

NACRES:

NA.24

质量水平

100

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

forensics and toxicology
pharmaceutical (small molecule)

储存温度

2-8°C

SMILES字符串

Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1

InChI

1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)

InChI key

JLKIGFTWXXRPMT-UHFFFAOYSA-N

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一般描述

磺胺甲恶唑是抑菌抗生素，属于磺胺类。广泛用于治疗肺囊虫病、球虫病、胃肠炎、腹泻和呼吸系统疾病（如肺炎等）。

应用

有关合适仪器技术的更多信息，请参考产品的分析证书。如需进一步支持，请联系技术服务。

磺胺甲恶唑用作分析参考标准品，使用分析和微生物测定技术，定量牛乳样品中的分析物。

生化/生理作用

通过抑制二氢叶酸合成酶阻断二氢叶酸合成的磺胺类抗生素。
作用方式：在原核生物中抑制叶酸合成。
抗菌谱：革兰氏阳性菌、革兰氏阴性菌、衣原体
抗性机理：二氢叶酸合成酶或叶酸合成替代路径的改变。

象形图

GHS08,GHS09

警示用语：

Warning

危险声明

H361fd,H411

预防措施声明

P202 - P273 - P280 - P308 + P313 - P391 - P405

危险分类

Aquatic Chronic 2 - Repr. 2

WGK

WGK 2

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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分析证书(COA)

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Drugs: Synonyms and Properties (2017)

Use of chemometric techniques to design a microbiological method for sulfonamide detection in milk

Nagel.GO, et al.

Czech Journal of Food Sciences, 31(6), 627-632 (2013)

Sulfamethoxazole abatement by means of ozonation

Journal of Hazardous Materials, 150(3), 790-794 (2008)

Impact of humic acid fouling on membrane performance and transport of pharmaceutically active compounds in forward osmosis.

Ming Xie et al.

Water research, 47(13), 4567-4575 (2013-06-15)

The impact of humic acid fouling on the membrane transport of two pharmaceutically active compounds (PhACs) - namely carbamazepine and sulfamethoxazole - in forward osmosis (FO) was investigated. Deposition of humic acid onto the membrane surface was promoted by the

Prevalence of sulfonamide-resistant bacteria, resistance genes and integron-associated horizontal gene transfer in natural water bodies and soils adjacent to a swine feedlot in northern Taiwan.

Jih-Tay Hsu et al.

Journal of hazardous materials, 277, 34-43 (2014-03-19)

Antibiotics are commonly used in swine feed to treat and prevent disease, as well as to promote growth. Antibiotics released into the environment via wastewater could accelerate the emergence of antibiotic-resistant bacteria and resistance genes in the surrounding environment. In

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