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Merck
CN

S7007

Supelco

磺胺地索辛

98.0-102.0%

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别名:
4-氨基-N-(2,6-二甲氧-4-嘧啶基)苯磺酰胺
经验公式(希尔记法):
C12H14N4O4S
CAS号:
分子量:
310.33
Beilstein:
306856
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

质量水平

检测方案

98.0-102.0%

形式

powder

技术

HPLC: suitable
gas chromatography (GC): suitable

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria

应用

forensics and toxicology
pharmaceutical (small molecule)

作用机制

DNA synthesis | interferes
enzyme | inhibits

储存温度

2-8°C

SMILES字符串

COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1

InChI

1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)

InChI key

ZZORFUFYDOWNEF-UHFFFAOYSA-N

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一般描述

化学结构:磺胺

应用

有关适用仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务部门。

生化/生理作用

通过抑制二氢叶酸合成酶阻断二氢叶酸合成的磺胺类抗生素。
作用方式:在原核生物中抑制叶酸合成。
抗菌谱:革兰氏阳性菌、革兰氏阴性菌、衣原体
抗性机理:二氢叶酸合成酶或叶酸合成替代路径的改变。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


分析证书(COA)

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Annie von Eyken et al.
Journal of the American Society for Mass Spectrometry, 30(5), 765-777 (2019-03-17)
Non-targeted screening (e.g., suspected-target) is emerging as an attractive tool to investigate the occurrence of contaminants in food. The sample preparation and instrument analysis steps are known to influence the identification of analytes with non-targeted workflows, especially for complex matrices.
Dan Liu et al.
Chemical & pharmaceutical bulletin, 59(1), 63-71 (2011-01-08)
Recently, dendrimers have been widely used in medical applications such as drug delivery and gene transfection. In this study, a pH-sensitive diblock copolymer of poly(methacryloyl sulfadimethoxine) (PSD) and polyethylene glycol (PEG) modified by lactose (LA-PEG-b-PSD) was synthesized. The pK(a) value
Hiroichi Ozaki et al.
Veterinary microbiology, 150(1-2), 132-139 (2011-01-15)
To investigate the effects of rearing practices of commercial broiler chickens on the incidence of antimicrobial resistance in commensal Escherichia coli isolates, fecal E. coli isolates obtained in 4 farms were screened for anitimicrobial resistance. Ten E. coli isolates were
Ailiang Chen et al.
Biosensors & bioelectronics, 42, 419-425 (2012-12-12)
Quickly and sensitively detection of antibiotic residues in animal products often requires time-consuming techniques and expensive instrumentation. To address these limitations, a high sensitive aptasensor for sulfadimethoxine (SDM) using unmodified gold nanoparticles (AuNPs) was developed in the present study. The
Lou Ann Tom et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 909, 61-64 (2012-11-17)
Four non-covalently prepared molecularly imprinted polymers (MIPs) for sulfadimethoxine (SDM) were prepared using different ratios of SDM template, methacrylic acid monomer, and ethylene glycol dimethacrylate cross-linker. The imprinting factor (IF) was calculated by comparing the retention of SDM on the

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