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Merck
CN

S2050000

磺胺甲二唑

European Pharmacopoeia (EP) Reference Standard

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别名:
4-氨基-N-(5-甲基-1,3,4-噻二唑-2-基)苯磺酰胺, N1-(5-甲基-1,3,4-噻二唑-2-基)磺胺
经验公式(希尔记法):
C9H10N4O2S2
CAS号:
分子量:
270.33
Beilstein:
255002
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

sulfamethizole

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES字符串

Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1

InChI

1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)

InChI key

VACCAVUAMIDAGB-UHFFFAOYSA-N

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一般描述

Sulfamethizole is a sulfonamide derivative used as an antimicrobial drug for the prevention and cure of bacterial infections in both humans and animals.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

象形图

Exclamation mark

警示用语:

Warning

危险声明

预防措施声明

危险分类

Skin Sens. 1

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Solubility of sulfamethizole in some propylene glycol+ water mixtures at several temperatures.
Delgado D R, et al.
Fluid Phase Equilibria, 322, 113-119 (2012)
Susceptibility of Danish Escherichia coli strains isolated from urinary tract infections and bacteraemia, and distribution of sul genes conferring sulphonamide resistance.
Kerrn M B, et al.
The Journal of Antimicrobial Chemotherapy, 50(4), 513-516 (2002)
Adrian I Campos et al.
Molecular cell, 74(6), 1291-1303 (2019-05-03)
Alternative to the conventional search for single-target, single-compound treatments, combination therapies can open entirely new opportunities to fight antibiotic resistance. However, combinatorial complexity prohibits experimental testing of drug combinations on a large scale, and methods to rationally design combination therapies
Images in clinical medicine. Actinomycetoma.
Manuelle Viguier et al.
The New England journal of medicine, 372(3), 264-264 (2015-01-15)
Yong-Gang Zhao et al.
Journal of chromatography. A, 1345, 17-28 (2014-05-02)
A novel, simple and sensitive method was developed for the simultaneous determination of 22 sulfonamides (SAs) in chicken breast muscle by using the dispersive micro-solid-phase extraction (d-μ-SPE) procedure combined with ultra-fast liquid chromatography-tandem quadrupole mass spectrometry (UFLC-MS/MS). The excellent core-shell

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