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Merck
CN

S100

米赛林 盐酸盐

analytical standard, for drug analysis

别名:

1,2,3,4,10,14b-六氢-2-甲基-二苯并[c,f]吡嗪并[1,2-a]氮杂卓 盐酸盐

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关于此项目

经验公式(希尔记法):
C18H20N2 · HCl
化学文摘社编号:
分子量:
300.83
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
244-426-7
MDL number:
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InChI key

YNPFMWCWRVTGKJ-UHFFFAOYSA-N

InChI

1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H

SMILES string

Cl.CN1CCN2C(C1)c3ccccc3Cc4ccccc24

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

solubility

H2O: 3.4 mg/mL, ethanol: 5.6 mg/mL

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Antidepressant; antagonist/inverse agonist at 5-HT2 serotonin receptors; also blocks the H1 histamine receptor and the α2 adrenoceptor.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

13 - Non Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Marike van Lingen et al.
Frontiers in cell and developmental biology, 7, 65-65 (2019-05-21)
Serotonin (5-HT) is a crucial signal in the neurogenic niche microenvironment. Dysregulation of the 5-HT system leads to mood disorders but also to changes in appetite and metabolic rate. Tryptophan hydroxylase 2-deficient (Tph2-/- ) mice depleted of brain 5-HT display
A C de Luca et al.
Journal of tissue engineering and regenerative medicine, 12(3), 676-686 (2017-05-31)
Adipose-derived stem cells (ASC) are becoming one of the most exploited cells in peripheral nerve repair. They are fast-growing and able to protect neurons from apoptosis; they can reduce post-injury latency and the risk of muscle atrophy. This study evaluates
Yun Gu et al.
Frontiers in pharmacology, 9, 1026-1026 (2018-10-26)
Remyelination is critical for nerve regeneration. However, the molecular mechanism involved in remyelination is poorly understood. To explore the roles of 17β-estradiol (E2) for myelination in the peripheral nervous system, we used a co-culture model of rat dorsal root ganglion
Choongjin Ban et al.
Food chemistry, 302, 125328-125328 (2019-08-14)
To control the oral bioavailability of curcumin, we fabricated solid lipid nanoparticles (SLNs) using tristearin and polyethylene glycol (PEG)ylated emulsifiers. Lipolysis of prepared SLNs via simulated gastrointestinal digestion was modulated by altering the types and concentrations of emulsifiers. After digestion
Marij Zuidersma et al.
Journal of psychosomatic research, 74(1), 25-30 (2013-01-01)
Evaluating the effects of implementing an antidepressant treatment strategy in depressed myocardial infarction (MI)-patients on long-term cardiovascular outcomes and all-cause mortality. MI-patients were evaluated for the presence of a diagnosis of post-MI depression at 3, 6, 9 and 12months after

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