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线性分子式:
C23H14O11Na2
化学文摘社编号:
分子量:
512.33
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
产品名称
色甘酸钠, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C23H16O11.Na.H/c24-11(9-31-14-3-1-5-16-20(14)12(25)7-18(33-16)22(27)28)10-32-15-4-2-6-17-21(15)13(26)8-19(34-17)23(29)30;;/h1-8,11,24H,9-10H2,(H,27,28)(H,29,30);;
SMILES string
[Na].OC(COc1cccc2OC(=CC(=O)c12)C(O)=O)COc3cccc4OC(=CC(=O)c34)C(O)=O
InChI key
UXMUBZWVLQEMRB-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
sodium cromoglicate
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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Biochem/physiol Actions
色甘酸钠阻断肥大细胞释放组胺和其他促炎介质。
Application
Sodium cromoglicate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Validated RP-HPLC method for estimation of sodium cromoglycate in human plasma.
Sowjanya P.
International Journal of Pharmaceutical Research and Development, 5, 112-120 (2013)
Effects of sodium cromoglycate on cytokine production following antigen stimulation of a passively sensitized human lung model.
Matsuo N, et al.
Annals of Allergy, Asthma & Immunology, 84(1), 72-78 (2000)
Development and validation of impurity-profiling UPLC method for the determination of sodium cromoglicate and tetryzoline hydrochloride: Application on rabbit aqueous humor.
Lotfy HM, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1006, 121-129 (2015)
Eyal Zur
International journal of pharmaceutical compounding, 16(5), 386-393 (2012-10-18)
Sodium cromoglicate (cromolyn sodium) is a very well-known medicine that has been used for many years for various allergic conditions. The topical use of this medicine is less known, and there are no commercial medicines of cream, gel, or lotion
Lindsey L Kennedy et al.
Laboratory investigation; a journal of technical methods and pathology, 94(12), 1406-1418 (2014-11-05)
Cholangiopathies are characterized by dysregulation of the balance between biliary growth and loss. We have shown that histamine (HA) stimulates biliary growth via autocrine mechanisms. To evaluate the paracrine effects of mast cell (MC) stabilization on biliary proliferation, sham or
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