氯化乙酰胆碱

Acetylcholine Chloride, the chloride salt of acetylcholine, is a synthetic amino alcohol with cholinergic properties, making it a vital component in biochemical and neurotransmission studies. It replicates the effects of the endogenous acetylcholine compound, which plays a significant role in the immune system, inflammation, and allergy research. Acetylcholine chloride acts as a cholinergic neurotransmitter, binding to nicotinic and muscarinic acetylcholine receptors, facilitating the opening of calcium channels.Furthermore, Acetylcholine chloride (ACh chloride) functions as a potent cholinergic agonist, influencing the activity of dopaminergic (DAergic) neurons by stimulating nicotinic acetylcholine receptors (nAChRs). This feature is particularly relevant in studies related to the immune system and inflammation. Additionally, it demonstrates the capacity to inhibit the aggregation of p53 mutant peptide in vitro, which contributes to the exploration of biochemical and allergy research.

Acetylcholine chloride has been used:

• as an agent to trigger sudomotor axon reflex response during autonomic test
• to induce contraction amplitude of pyloric circular smooth muscle strip (PCSMS) in rats
• as a substrate for acetylcholinesterase
• to stimulate after discharge in Aplysia bag cell neurons

氯化乙酰胆碱，20mg/kg体重注射，减少小鼠实验性诱发脓毒病的死亡和血浆促炎细胞因子。类胆碱能抗-炎症机制可能通过乙酰胆碱和 α7n单核细胞，巨噬细胞和中性粒细胞上的胆红素受体互作接待，降低了促炎细胞活素，比如 TNF-α,IL-1β,和IL-6。

胆碱能突触中的内源性神经递质，通过增强肌膜动作电位来触发肌肉收缩反应。

非常吸湿

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