PHR3029
洛莫司汀
pharmaceutical secondary standard, certified reference material
别名:
Lomustine, 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
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关于此项目
经验公式（希尔记法）:
C9H16ClN3O2
化学文摘社编号:
分子量:
233.70
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
产品名称
洛莫司汀, pharmaceutical secondary standard, certified reference material
InChI
1S/C9H16ClN3O2/c10-6-7-13(12-15)9(14)11-8-4-2-1-3-5-8/h8H,1-7H2,(H,11,14)
SMILES string
ClCCN(N=O)C(=O)NC1CCCCC1
InChI key
GQYIWUVLTXOXAJ-UHFFFAOYSA-N
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to USP 1369419
API family
lomustine
CofA
current certificate can be downloaded
packaging
pkg of 500 mg
manufacturer/tradename
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
application(s)
pharmaceutical
storage temp.
2-8°C
Quality Level
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Biochem/physiol Actions
Antineoplastic agent with cellular DNA effects. Lomustine induces p53 expression in A2870 cells.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
General description
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Lomustine can be used in quantitative determination of analyte in rat plasma using HPLC/UV) method. It can also be used as a reference standard in the determination of lomustine capsules.
Lomustine can be used in quantitative determination of analyte in rat plasma using HPLC/UV) method. It can also be used as a reference standard in the determination of lomustine capsules.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Carc. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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