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Merck
CN

PHR2631

Supelco

L-α-溶血磷脂酰胆碱 来源于鸡蛋黄

Pharmaceutical Secondary Standard; Certified Reference Material

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别名:
1-酰基-sn-甘油-3-磷酸胆碱, L-α-Lysolecithin
CAS号:
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to Ph. Eur. Y0001904
traceable to USP 1372050

API类

lysophosphatidylcholine

形式

solid

包装

pkg of 250 mg

应用

pharmaceutical small molecule

储存温度

-10 to -25°C

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一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

溶血卵磷脂为氧化型低密度脂蛋白的主要成分,并且与多种炎症反应包括动脉粥样硬化有关。用于使脊髓神经元脱髓鞘以及研究作为髓鞘再生基础的过程。它可激活蛋白激酶 C、p38 MAP 激酶、p42 MAP 激酶和 jun 激酶 (JNK) 途径,以及激活 c-jun 的转录。溶血卵磷脂在心肌缺血过程中积累并可能通过对细胞间隙连接通讯的解偶联诱发心率失常,以及通过提高心肌细胞的 Na+ 负荷增加缺血性损伤。它还可激活 TREK1、TREK2 和 TRAAK K+ 通道。

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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