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Merck
CN
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主要文件

PHR2016

Supelco

奥美沙坦酯相关化合物A

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

3,6-Dihydro-6,6-dimethyl-2-propyl-3-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-4H-furo[3,4-d]imidazol-4-one, 1-{[2′-(1H-Tetrazol-5-yl)biphenyl-4-yl]methyl}-4,4-dimethyl-2-propyl-1H-furo[3,4-d]imidazol-6(4H)-one

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About This Item

经验公式（希尔记法）:
C24H24N6O2
CAS号:
849206-43-5
分子量:
428.49
UNSPSC代码:
41116107
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to USP 1478378

API类

olmesartan

CofA

current certificate can be downloaded

包装

pkg of 40 mg

应用

pharmaceutical

包装形式

neat

储存温度

-10 to -25°C

SMILES字符串

[nH]1nnnc1c2c(cccc2)c3ccc(cc3)C[n]4c5c(nc4CCC)C(OC5=O)(C)C

InChI

1S/C24H24N6O2/c1-4-7-19-25-21-20(23(31)32-24(21,2)3)30(19)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22-26-28-29-27-22/h5-6,8-13H,4,7,14H2,1-3H3,(H,26,27,28,29)

InChI key

JUQNVWFXORBZQJ-UHFFFAOYSA-N

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相关类别

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Olmesartan Medoxomil Related Compound A is found as an impurity of olmesartan medoxomil. Olmesartan medoxomil is a specific angiotensin II type 1 antagonist, which is widely used as an antihypertensive agent for the treatment of hypertension.

应用

Olmesartan medoxomil may be used as a secondary pharma standard for the determination of the analyte in pharmaceutical formulations using different analytical techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAB5323 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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Validated absorption factor spectrophotometric and reversed-phase high-performance liquid chromatographic methods for the determination of ramipril and olmesartan medoxomil in pharmaceutical formulations
Patel VC, et al.
Eurasian Journal of Analytical Chemistry, 2(3), 159-171 (2007)
Simultaneous determination of olmesartan medoxomil and irbesartan and hydrochlorothiazide in pharmaceutical formulations and human serum using high performance liquid chromatography
Sultana N, et al.
Se Pu / Chinese Journal of Chromatography, 26(5), 544-549 (2008)

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