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Merck
CN

PHR1964

Supelco

布洛芬杂质F

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

3-(4-Isobutylphenyl)propionic acid, 3-[4-(2-METHYLPROPYL)PHENYL] PROPANOIC ACID

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About This Item

经验公式(希尔记法):
C13H18O2
CAS号:
分子量:
206.28
UNSPSC代码:
41116107
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to Ph. Eur. Y0000140

API类

ibuprofen

CofA

current certificate can be downloaded

包装

pkg of 30 mg

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

InChI

1S/C13H18O2/c1-10(2)9-12-5-3-11(4-6-12)7-8-13(14)15/h3-6,10H,7-9H2,1-2H3,(H,14,15)

InChI key

DYNVRFFVBZVRND-UHFFFAOYSA-N

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一般描述

Ibuprofen Impurity F is an impurity of the drug, ibuprofen. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that is effective against pain, inflammation and fever. It is deemed as a safe drug on account of its reversible inhibitory effects on cyclooxygenase (COX) enzyme along with its unique pharmacokinetics.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Ibuprofen may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by analytical techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAB2590 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

相关产品

产品编号
说明
价格

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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Determination of enantiomeric composition of ibuprofen in pharmaceutical formulations by partial least-squares regression of strongly overlapped chromatographic profiles
Grisales JO, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 910, 78-83 (2012)
Two liquid chromatographic methods for the simultaneous determination of ibuprofen and methocarbamol or chlorzoxazone in the presence of their degradation products
Elkady EF and Fouad MA
Journal of Liquid Chromatography and Related Technologies, 35(7), 882-895 (2012)
Ibuprofen: A critical bibliographic review (1999)
Ibuprofen
USP42-NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 34(4), 2232-2232 (2018)

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