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Merck
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安全信息

PHR1950

Supelco

螺旋霉素

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

螺旋霉素

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About This Item

CAS号:
8025-81-8
EC 号:
232-429-6
MDL编号:
MFCD01314545
UNSPSC代码:
41116107
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to Ph. Eur. S1100000

API类

spiramycin

CofA

current certificate can be downloaded

包装

pkg of 500 mg

应用

pharmaceutical

格式

neat

储存温度

-10 to -25°C

SMILES字符串

CO[C@H]1[C@H](O)CC(=O)O[C@H](C)C\C=C\C=C\[C@H](OC2CCC(C(C)O2)N(C)C)[C@H](C)C[C@H](CC=O)[C@@H]1OC3OC(C)C(OC4CC(C)(O)C(O)C(C)O4)C(C3O)N(C)C

InChI

1S/C43H74N2O14/c1-24-21-29(19-20-46)39(59-42-37(49)36(45(9)10)38(27(4)56-42)58-35-23-43(6,51)41(50)28(5)55-35)40(52-11)31(47)22-33(48)53-25(2)15-13-12-14-16-32(24)57-34-18-17-30(44(7)8)26(3)54-34/h12-14,16,20,24-32,34-42,47,49-51H,15,17-19,21-23H2,1-11H3/b13-12+,16-14+/t24-,25-,26?,27?,28?,29+,30?,31-,32+,34?,35?,36?,37?,38?,39+,40+,41?,42?,43?/m1/s1

InChI key

ACTOXUHEUCPTEW-JMRHEKERSA-N

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相关类别

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Spiramycin belongs to the macrolide group of antibiotics, widely used in the treatment of respiratory tract, skin and skin-structure, sexually transmitted, and various other infections. Spiramycin is derived from the culture filtrate of Streptomyces ambofaciens and its mode of action involves the exibition of antimicrobial activity by inhibiting ribosomal protein biosynthesis.

应用

Spiramycin may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using liquid chromatography technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAB1418 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

相关产品

产品编号
说明
价格

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

Choose from one of the most recent versions:

分析证书(COA)

Lot/Batch Number
LRAC9868
LRAC8838
LRAB1418

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Separation and determination of components of spiramycin in bulk powders and in pharmaceutical preparations by high-performance liquid chromatography
Bens AG, et al.
Chromatographia, 12(5), 294-298 (1979)
LC determination and stability assessment of macrolide antibiotics azithromycin and spiramycin in bulk and tablet samples
Mahmoudi A
International Letters of Natural Sciences, 47(5), 294-298 (2015)

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