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Merck
CN

PHR1930

Supelco

乙胺丁醇

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

乙胺丁醇 二盐酸盐, 2,2#8242;-(1,2- Ethanediyldiimino)-1-丁醇 二盐酸盐, Emb

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About This Item

经验公式(希尔记法):
C10H24N2O2 · 2HCl
CAS号:
分子量:
277.23
EC 号:
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to Ph. Eur. E1850000
traceable to USP 1257007

API类

ethambutol

形式

powder

CofA

current certificate can be downloaded

包装

pkg of 500 mg

应用

pharmaceutical

储存温度

2-30°C

SMILES字符串

CC[C@@H](CO)NCCN[C@H](CO)CC.Cl.Cl

InChI

1S/C10H24N2O2.2ClH/c1-3-9(7-13)11-5-6-12-10(4-2)8-14;;/h9-14H,3-8H2,1-2H3;2*1H/t9-,10-;;/m0../s1

InChI key

AUAHHJJRFHRVPV-BZDVOYDHSA-N

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一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

应用

乙胺丁醇是一种分枝杆菌抗菌剂,与其他抗生素联合使用可治疗结核病,减缓耐药性的发展进程。在中国结核病发病率最高的地区,长期用于研究耐多药结核病(MDR-TB)。

生化/生理作用

乙胺丁醇对活跃生长的结核杆菌具有抗菌作用。分枝菌酸附着在阿拉伯半乳聚糖的 D-阿拉伯糖残基的 5′-羟基上,并在细胞壁中形成分枝酸- 阿拉伯半乳糖-肽聚糖复合层。乙胺丁醇通过抑制阿拉伯糖基转移酶,特别是分枝杆菌中的阿拉伯糖基转移酶,干扰阿拉伯半乳聚糖的合成,通过干扰分枝杆菌细胞壁中的阿拉伯半乳聚糖的生物合成,并导致细胞壁渗透性增加。

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAB0956 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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分析证书(COA)

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