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主要文件

COO原产地证书/COA分析证书

PHR1903

西酞普兰相关化合物D

Name: 西酞普兰相关化合物D
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

Citalopram Related Compound D, 1-(4-Fluorophenyl)-1-(3-methylaminopropyl)-1,3-dihydroisobenzofuran-5-carbonitrile hydrochloride, 1-(4-Fluorophenyl)-1-(3-methylamino)propyl)-1,3-dihydroisobenzofuran-5-carbonitrile hydrochloride

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About This Item

经验公式（希尔记法）:

C₁₉H₁₉FN₂O · HCl

CAS号:

97743-99-2

分子量:

346.83

UNSPSC代码:

41116107

NACRES:

NA.24

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USP

1134277

Citalopram Related Compound D

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PHR1904

西酞普兰相关化合物E

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PHR1308

盐酸普萘洛尔

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草酸艾司西酞普兰

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盐酸舍曲林盐酸盐

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对乙酰氨基酚

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PHR1380

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等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to USP 1134277

API类

citalopram

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-30°C

SMILES字符串

Fc1ccc(cc1)C2(OCc3c2ccc(c3)C#N)CCCNC.Br

InChI

1S/C19H19FN2O.BrH/c1-22-10-2-9-19(16-4-6-17(20)7-5-16)18-8-3-14(12-21)11-15(18)13-23-19;/h3-8,11,22H,2,9-10,13H2,1H3;1H

InChI key

DJCAYVHVPUEMQJ-UHFFFAOYSA-N

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一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Citalopram Related Compound D is a related impurity found in the drug citalopram. Citalopram is a racemic bicyclic phthalane derivative and is a potent anti-depressant drug, that acts by inhibition of serotonin uptake.

应用

Citalopram Related Compound D may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAB0345 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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Development and optimization of an HPLC analysis of citalopram and its four nonchiral impurities using experimental design methodology

Tadi T, et al.

Journal of AOAC (Association of Official Analytical Chemists) International, 95(3), 733-743 (2012)

Semi-preparative isolation and structural elucidation of an impurity in citalopram by LC/MS/MS

Raman B, et al.

Journal of Pharmaceutical and Biomedical Analysis, 50(3), 377-383 (2009)

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主要文件

西酞普兰相关化合物D

Pharmaceutical Secondary Standard; Certified Reference Material

About This Item

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属性

等级

质量水平

Agency

API类

CofA

技术

应用

包装形式

储存温度

SMILES字符串

InChI

InChI key

相关类别

说明

一般描述

应用

分析说明

其他说明

附注

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相关产品

相关产品

安全信息

储存分类代码

WGK

闪点(°F)

闪点(°C)

文件

分析证书(COA)

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