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![Methyl5-[2-[benzyl(tert-butyl)amino]acetyl]-2-hydroxybenzoate hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material](/deepweb/assets/sigmaaldrich/product/images/192/011/45a62463-4dd5-4639-8d62-60c6e919308a/640/45a62463-4dd5-4639-8d62-60c6e919308a.jpg)
等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to USP 1269061
API类
exemestane
CofA
current certificate can be downloaded
包装
pkg of 30 mg
应用
pharmaceutical
包装形式
neat
储存温度
2-8°C
SMILES字符串
O=C1[C@@]2([C@H]([C@H]3[C@@H]([C@]4(CCC(=O)C=C4C(=C)C3)C)CC2)CC1)C
InChI
1S/C20H26O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h11,14-16H,1,4-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1
InChI key
KQRGETZTRARSMA-DAELLWKTSA-N
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一般描述
Exemestane Related Compound A is an impurity of the steroidal anticancer drug, exemestane. Exemestane belongs to the class of antiestrogens known as aromatase inhibitors. It is commonly used for the treatment of breast cancer.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
应用
Exemestane may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
分析说明
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAB0339 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
相关产品
产品编号
说明
价格
Development and validation of a stability indicating LC method for the assay and related substances determination of Exemestane, an aromatase inhibitor
Kumar RS, et al.
Journal of Pharmaceutical and Biomedical Analysis, 50(5), 746-752 (2009)
Analytical method validation for HPLC assay of oral anticancer drug exemestane
Yavuz B
FABAD Journal of Pharmaceutical Sciences, 32(1), 15-15 (2007)
Exemestane: a review of its clinical efficacy and safety
L?nning PE
Breast (Edinburgh, Scotland), 10(3), 198-208 (2001)
A novel validated stability-indicating RP-HPLC method for the determination of Exemestane (steroidal aromatase inhibitor)
Mukthinuthalapati MA and Bukkapatnam V
Journal of Bioequivalence & Bioavailability, 7(6), 288-288 (2015)
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