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等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to Ph. Eur. Y0001188
API类
tiotropium
CofA
current certificate can be downloaded
包装
pkg of 50 mg
应用
pharmaceutical
格式
neat
储存温度
2-8°C
InChI
1S/C19H22NO4S2.BrH.H2O/c1-20(2)12-9-11(10-13(20)17-16(12)24-17)23-18(21)19(22,14-5-3-7-25-14)15-6-4-8-26-15;;/h3-8,11-13,16-17,22H,9-10H2,1-2H3;1H;1H2/q+1;;/p-1/t11?,12-,13+,16-,17+;;
InChI key
MQLXPRBEAHBZTK-KFEMZTBUSA-M
一般描述
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Tiotropium bromide monohydrate is structurally related to ipratropium bromide. It is a second-generation anticholinergic agent specific for muscarinic receptors (M1, M2 & M3) in humans.
应用
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Tiotropium bromide monohydrate may be used as a reference compound to investigate the role of M2 and M3 muscarinic receptors in the contraction of rat and human small airways.
分析说明
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAB0347 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
A role for M2 and M3 muscarinic receptors in the contraction of rat and human small airways.
Brown S M, et al.
European Journal of Pharmacology, 702(1-3), 109-115 (2013)
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