所有图片(1)

文件

PHR1851

奥美沙坦酯

Name: 奥美沙坦酯
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

Olmesartan medoxomil

登录查看公司和协议定价

所有图片(1)

About This Item

经验公式（希尔记法）:

C₂₉H₃₀N₆O₆

CAS号:

144689-63-4

分子量:

558.59

MDL编号:

MFCD00944911

UNSPSC代码:

41116107

NACRES:

NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP 1173
traceable to Ph. Eur. Y0001405
traceable to USP 1478367

API类

olmesartan

CofA

current certificate can be downloaded

包装

pkg of 200 mg

应用

pharmaceutical

格式

neat

储存温度

-10 to -25°C

SMILES字符串

CCCC1=NC(C(O)(C)C)=C(C(OCC2=C(C)OC(O2)=O)=O)N1CC(C=C3)=CC=C3C4=CC=CC=C4C5=NN=NN5

InChI

1S/C29H30N6O6/c1-5-8-23-30-25(29(3,4)38)24(27(36)39-16-22-17(2)40-28(37)41-22)35(23)15-18-11-13-19(14-12-18)20-9-6-7-10-21(20)26-31-33-34-32-26/h6-7,9-14,38H,5,8,15-16H2,1-4H3,(H,31,32,33,34)

InChI key

UQGKUQLKSCSZGY-UHFFFAOYSA-N

基因信息

human ... AGTR1(185)

正在寻找类似产品? 访问产品对比指南

一般描述

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Olmesartan Medoxomil is an AT₁ subtype angiotensin-II receptor antagonist used in the management of hypertension. It prevents angiotensin II from binding to the AT₁ receptors, thereby decreasing vasoconstriction.

应用

Theis pharmaceutical secondary standard can also be used as follows:

Development and validation of an isocratic ultra-high performance liquid chromatography (UHPLC) based stability indicating method to determine olmesartan medoxomil and amlodipine besylate in combined tablet dosage forms
Simultaneous determination of Olmesartan medoxomil and chlorthalidone by reversed phase-high performance liquid chromatography (RP-HPLC) in tablets
Quantification of olmesartan medoxomil and its degradation products in bulk drugs and pharmaceutical formulations by using a systematic quality by design (QbD)-based reverse-phase liquid chromatography method
Reversed phase-high performance liquid chromatographic (RP-HPLC) analysis of olmesartan medoxomil and hydrochlorothiazide in their combined tablet dosage form
Determination of olmesartan medoxomil and amlodipine besylate in their combined tablet dosage form by absorption subtraction method, ratio subtraction with extended ratio subtraction method, dual wavelength technique, and second order derivative spectrophotometry

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

附注

To see an example of a Certificate of Analysis for this material enter LRAC2529 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.