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等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to USP 1680030
描述
Pharmaceutical Secondary Standard; Certified Reference Material
API类
triamterene
CofA
current certificate can be downloaded
包装
pkg of 100 mg
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
[nH]1c2nc(nc(c2nc([c]1=O)c3ccccc3)N)N
InChI
1S/C12H10N6O/c13-9-8-10(18-12(14)16-9)17-11(19)7(15-8)6-4-2-1-3-5-6/h1-5H,(H5,13,14,16,17,18,19)
InChI key
USTXKGPQJJRCTO-UHFFFAOYSA-N
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一般描述
Triamterene Related Compound C is a pharmaceutical impurity of a potassium-sparing diuretic, triamterene. Triamterene exhibits antihypertensive activity. It is used in combination with thiazide deuretic, such as benzthiazide for treating hypertension and edema associated with mild to moderate congestive heart failure.
应用
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Triamterene may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using reversed-phase high-performance liquid chromatography technique.
分析说明
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAB0841 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
High performance liquid chromatography for simultaneous determination of xipamide, triamterene and hydrochlorothiazide in bulk drug samples and dosage forms
El-Hay ASS, et al.
Acta pharmaceutica, 66(1), 109-118 (2016)
Development and Validation of RP-HPLC Method for Simultaneous Estimation of Triamterene and Benzthiazide in Tablets
Chauhan CV, et al.
PharmaTutor, 2(6), 115-122 (2014)
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