PHR1795
亚氨基联苄
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
亚胺联苄, 10,11-二氢-5H-二苯并[b,f]氮杂卓
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经验公式（希尔记法）:
C14H13N
化学文摘社编号:
分子量:
195.26
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
207-787-1
Beilstein/REAXYS Number:
152732
MDL number:
产品名称
亚氨基联苄, Pharmaceutical Secondary Standard; Certified Reference Material
InChI key
ZSMRRZONCYIFNB-UHFFFAOYSA-N
InChI
1S/C14H13N/c1-3-7-13-11(5-1)9-10-12-6-2-4-8-14(12)15-13/h1-8,15H,9-10H2
SMILES string
C1Cc2ccccc2Nc3ccccc13
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to USP 1337004
API family
iminodibenzyl
CofA
current certificate can be downloaded
packaging
pkg of 100 mg
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
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Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Application
Iminodibenzyl may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by thin layer chromatography and spectrophotometry techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA8622 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Impurities in drugs I: Imipramine, desipramine, and their formulations.
McErlane KM, et al.
Journal of Pharmaceutical Sciences, 66(7), 1015-1018 (1977)
B A el-Zeany et al.
Journal of pharmaceutical and biomedical analysis, 33(4), 775-782 (2003-11-19)
Two spectrophotometric methods for the determination of imipramine in presence of iminodibenzyl as an impurity are described. The first method is a ratio-spectra first derivative spectrophotometry, the signals were measured at 240.2 nm for imipramine. Calibration graph was found linear
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