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PHR1773

Supelco

雷尼替丁相关化合物A

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

2-{{{5-[(Dimethylamino)methyl]furan-2-yl}methyl}sulfanyl}ethanamine hemifumarate salt, 2-{{{5-[(DIMETHYLAMINO)METHYL] FURAN-2-YL}METHYL}SULFANYL} ETHANEAMINEHEMIFUMARATE SALT, Ranitidine Impurity B, 2-{{{5-[(Dimethylamino)methyl]-2-furanyl}methyl}thio}ethylamine hemifumarate salt, 5-{[(2-Aminoethyl)thio]methyl}-N,N-dimethyl- 2-furanmethanamine hemifumarate salt, Ranitidine diamine hemifumarate salt

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About This Item

经验公式（希尔记法）:
C10H18N2OS · 0.5 C4H4O4
CAS号:
91224-69-0
分子量:
272.36
UNSPSC代码:
41116107
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to USP 1598507

API类

ranitidine

CofA

current certificate can be downloaded

包装

pkg of 100 mg

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

OC(=O)\C=C\C(O)=O.CN(C)Cc1ccc(CSCCN)o1

InChI

1S/C10H18N2OS.C4H4O4/c1-12(2)7-9-3-4-10(13-9)8-14-6-5-11;5-3(6)1-2-4(7)8/h3-4H,5-8,11H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

InChI key

VKUKMWIQZWDCGK-WLHGVMLRSA-N

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相关类别

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ranitidine Related Compound A is an impurity of ranitidine, an inhibitor of gastric acid secretion. Ranitidine is widely used for treating gastric and duodenal ulcers.

应用

Ranitidine may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using kinetic spectrophotometric technique and electrochemical method.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC0714 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

相关产品

产品编号
说明
价格

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雷尼替丁 盐酸盐, United States Pharmacopeia (USP) Reference Standard

1598507

Ranitidine Related Compound A, United States Pharmacopeia (USP) Reference Standard

1598700

Ranitidine Related Compound C, United States Pharmacopeia (USP) Reference Standard

1598609

雷尼替丁相关化合物B, United States Pharmacopeia (USP) Reference Standard

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Y0000416

雷尼替丁杂质J, European Pharmacopoeia (EP) Reference Standard

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雷尼替丁 盐酸盐, European Pharmacopoeia (EP) Reference Standard

Y0001787

雷尼替丁杂质A, European Pharmacopoeia (EP) Reference Standard

PHR1774

雷尼替丁相关化合物B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1775

雷尼替丁相关化合物C, Pharmaceutical Secondary Standard; Certified Reference Material

BP471

雷尼替丁 盐酸盐, British Pharmacopoeia (BP) Reference Standard

PHR2180

雷尼替丁相关物质I, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2181

雷尼替丁相关物质J, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2179

雷尼替丁相关物质H, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2182

N-甲基-1-甲硫基-2-硝基乙烯胺, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2175

雷尼替丁相关物质D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2177

Ranitidine Impurity F

PHR2178

Ranitidine Impurity G, Pharmaceutical Secondary Standard; Certified Reference Material

储存分类代码

11 - Combustible Solids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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Kinetic spectrophotometric determination of nizatidine and ranitidine in pharmaceutical preparations
Hassan ME and Belal F
Journal of Pharmaceutical and Biomedical Analysis, 27(1-2), 31-38 (2002)
Simultaneous determination of ranitidine and metronidazole in pharmaceutical formulations at poly (chromotrope 2B) modified activated glassy carbon electrodes
Li X and Xu G
Journal of food and drug analysis, 22(3), 345-349 (2014)

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